Ductal recanalization and stenting for late presenters with TGA intact ventricular septum

Introduction: The ideal management strategy for patients presenting late with transposition of great arteries (TGA), intact ventricular septum (IVS), and regressed left ventricle (LV) is not clear. Primary switch, two-stage switch, and Senning operation are the options. Left ventricular retraining p...

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Main Authors: Shyam S Kothari, Sivasubramanian Ramakrishnan, Nagendra Boopathy Senguttuvan, Saurabh Kumar Gupta, Akshay K Bisoi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Annals of Pediatric Cardiology
Subjects:
Online Access:http://www.annalspc.com/article.asp?issn=0974-2069;year=2011;volume=4;issue=2;spage=135;epage=138;aulast=Kothari
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author Shyam S Kothari
Sivasubramanian Ramakrishnan
Nagendra Boopathy Senguttuvan
Saurabh Kumar Gupta
Akshay K Bisoi
author_facet Shyam S Kothari
Sivasubramanian Ramakrishnan
Nagendra Boopathy Senguttuvan
Saurabh Kumar Gupta
Akshay K Bisoi
author_sort Shyam S Kothari
collection DOAJ
description Introduction: The ideal management strategy for patients presenting late with transposition of great arteries (TGA), intact ventricular septum (IVS), and regressed left ventricle (LV) is not clear. Primary switch, two-stage switch, and Senning operation are the options. Left ventricular retraining prior to arterial switch by ductal stenting may be effective, but the experience is very limited. Methods: Five of six children aged 3-6 months with TGA-IVS and regressed LV underwent recanalization and transcatheter stenting of ductus arteriosus. The ductal stent was removed during arterial switch surgery. Results: The procedure was successful in 5/6 patients. All the patients had totally occluded ductus and needed recanalization with coronary total occlusion hardware. The ductus was dilated and stented with coronary stents. In all the patients, there was significant luminal narrowing despite adequate stent placement and deployment. Two patients needed reintervention for abrupt closure of the stent. Ductal stenting resulted in left ventricular preparedness within 7-14 days. One patient died of progressive sepsis after 14 days of stenting, even though the LV was prepared. Four patients underwent successful uneventful arterial switch surgery. During surgery, it was observed that the mucosal folds of duct were protruding through the struts of the stent in one patient. Conclusions: Ductal stenting is a good alternative strategy for left ventricular retraining in TGA with regressed LV even in patients with occluded ducts.
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spelling doaj.art-1828d32cb9ad4e7ba5271a01b94643092022-12-22T02:38:12ZengWolters Kluwer Medknow PublicationsAnnals of Pediatric Cardiology0974-20692011-01-014213513810.4103/0974-2069.84651Ductal recanalization and stenting for late presenters with TGA intact ventricular septumShyam S KothariSivasubramanian RamakrishnanNagendra Boopathy SenguttuvanSaurabh Kumar GuptaAkshay K BisoiIntroduction: The ideal management strategy for patients presenting late with transposition of great arteries (TGA), intact ventricular septum (IVS), and regressed left ventricle (LV) is not clear. Primary switch, two-stage switch, and Senning operation are the options. Left ventricular retraining prior to arterial switch by ductal stenting may be effective, but the experience is very limited. Methods: Five of six children aged 3-6 months with TGA-IVS and regressed LV underwent recanalization and transcatheter stenting of ductus arteriosus. The ductal stent was removed during arterial switch surgery. Results: The procedure was successful in 5/6 patients. All the patients had totally occluded ductus and needed recanalization with coronary total occlusion hardware. The ductus was dilated and stented with coronary stents. In all the patients, there was significant luminal narrowing despite adequate stent placement and deployment. Two patients needed reintervention for abrupt closure of the stent. Ductal stenting resulted in left ventricular preparedness within 7-14 days. One patient died of progressive sepsis after 14 days of stenting, even though the LV was prepared. Four patients underwent successful uneventful arterial switch surgery. During surgery, it was observed that the mucosal folds of duct were protruding through the struts of the stent in one patient. Conclusions: Ductal stenting is a good alternative strategy for left ventricular retraining in TGA with regressed LV even in patients with occluded ducts.http://www.annalspc.com/article.asp?issn=0974-2069;year=2011;volume=4;issue=2;spage=135;epage=138;aulast=KothariArterial switch surgeryductal stentingtransposition of the great arteries
spellingShingle Shyam S Kothari
Sivasubramanian Ramakrishnan
Nagendra Boopathy Senguttuvan
Saurabh Kumar Gupta
Akshay K Bisoi
Ductal recanalization and stenting for late presenters with TGA intact ventricular septum
Annals of Pediatric Cardiology
Arterial switch surgery
ductal stenting
transposition of the great arteries
title Ductal recanalization and stenting for late presenters with TGA intact ventricular septum
title_full Ductal recanalization and stenting for late presenters with TGA intact ventricular septum
title_fullStr Ductal recanalization and stenting for late presenters with TGA intact ventricular septum
title_full_unstemmed Ductal recanalization and stenting for late presenters with TGA intact ventricular septum
title_short Ductal recanalization and stenting for late presenters with TGA intact ventricular septum
title_sort ductal recanalization and stenting for late presenters with tga intact ventricular septum
topic Arterial switch surgery
ductal stenting
transposition of the great arteries
url http://www.annalspc.com/article.asp?issn=0974-2069;year=2011;volume=4;issue=2;spage=135;epage=138;aulast=Kothari
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AT nagendraboopathysenguttuvan ductalrecanalizationandstentingforlatepresenterswithtgaintactventricularseptum
AT saurabhkumargupta ductalrecanalizationandstentingforlatepresenterswithtgaintactventricularseptum
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