Preoperative preparation of hyperthyroidism for thyroidectomy – Role of supersaturated iodine and lithium carbonate

Introduction: Thyroidectomy is effective and safe procedure for permanent cure of hyperthyroidism (HT). Iodine preparations are widely used before operation to prevent excess blood loss. Ideal regimen for refractory HT is debated. This retrospective case–control study is designed to study the effica...

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Main Authors: Gopalakrishnan C Nair, Misha J C. Babu, Riju Menon, Pradeep Jacob
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Indian Journal of Endocrinology and Metabolism
Subjects:
Online Access:http://www.ijem.in/article.asp?issn=2230-8210;year=2018;volume=22;issue=3;spage=392;epage=396;aulast=Nair
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author Gopalakrishnan C Nair
Misha J C. Babu
Riju Menon
Pradeep Jacob
author_facet Gopalakrishnan C Nair
Misha J C. Babu
Riju Menon
Pradeep Jacob
author_sort Gopalakrishnan C Nair
collection DOAJ
description Introduction: Thyroidectomy is effective and safe procedure for permanent cure of hyperthyroidism (HT). Iodine preparations are widely used before operation to prevent excess blood loss. Ideal regimen for refractory HT is debated. This retrospective case–control study is designed to study the efficacy of various regimens of preoperative preparations. Materials and Methods: Case records, anesthesia charts, and follow-up details of hyperthyroid patients undergoing thyroidectomy were reviewed and compared with an age- and sex-matched euthyroid patients operated during the same period. Iodine preparations were not used for preoperative preparation. Study group was subdivided based on preoperative regimens of anti-thyroid medications. Results: Of the 168 patients in the study group, procedure time, duration of hospital stay, and overall complication rate were high compared to euthyroid group. Operative blood loss was not high in the study group. There was no difference in rate of complications in the subgroups of the study cohort. Conclusion: Iodine preparations are not mandatory in preoperative preparation of HT. Lithium carbonate is effective in preoperative preparation of refractory HT. Rate of postthyroidectomy complications is not different in patients receiving thionamides alone or in combination with β-blocker.
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spelling doaj.art-182c692781e948bf80b2b573300faf4e2022-12-21T18:49:41ZengWolters Kluwer Medknow PublicationsIndian Journal of Endocrinology and Metabolism2230-82102018-01-0122339239610.4103/ijem.IJEM_3_18Preoperative preparation of hyperthyroidism for thyroidectomy – Role of supersaturated iodine and lithium carbonateGopalakrishnan C NairMisha J C. BabuRiju MenonPradeep JacobIntroduction: Thyroidectomy is effective and safe procedure for permanent cure of hyperthyroidism (HT). Iodine preparations are widely used before operation to prevent excess blood loss. Ideal regimen for refractory HT is debated. This retrospective case–control study is designed to study the efficacy of various regimens of preoperative preparations. Materials and Methods: Case records, anesthesia charts, and follow-up details of hyperthyroid patients undergoing thyroidectomy were reviewed and compared with an age- and sex-matched euthyroid patients operated during the same period. Iodine preparations were not used for preoperative preparation. Study group was subdivided based on preoperative regimens of anti-thyroid medications. Results: Of the 168 patients in the study group, procedure time, duration of hospital stay, and overall complication rate were high compared to euthyroid group. Operative blood loss was not high in the study group. There was no difference in rate of complications in the subgroups of the study cohort. Conclusion: Iodine preparations are not mandatory in preoperative preparation of HT. Lithium carbonate is effective in preoperative preparation of refractory HT. Rate of postthyroidectomy complications is not different in patients receiving thionamides alone or in combination with β-blocker.http://www.ijem.in/article.asp?issn=2230-8210;year=2018;volume=22;issue=3;spage=392;epage=396;aulast=NairGraves' diseaselithium carbonateLugol's iodinetotal thyroidectomy
spellingShingle Gopalakrishnan C Nair
Misha J C. Babu
Riju Menon
Pradeep Jacob
Preoperative preparation of hyperthyroidism for thyroidectomy – Role of supersaturated iodine and lithium carbonate
Indian Journal of Endocrinology and Metabolism
Graves' disease
lithium carbonate
Lugol's iodine
total thyroidectomy
title Preoperative preparation of hyperthyroidism for thyroidectomy – Role of supersaturated iodine and lithium carbonate
title_full Preoperative preparation of hyperthyroidism for thyroidectomy – Role of supersaturated iodine and lithium carbonate
title_fullStr Preoperative preparation of hyperthyroidism for thyroidectomy – Role of supersaturated iodine and lithium carbonate
title_full_unstemmed Preoperative preparation of hyperthyroidism for thyroidectomy – Role of supersaturated iodine and lithium carbonate
title_short Preoperative preparation of hyperthyroidism for thyroidectomy – Role of supersaturated iodine and lithium carbonate
title_sort preoperative preparation of hyperthyroidism for thyroidectomy role of supersaturated iodine and lithium carbonate
topic Graves' disease
lithium carbonate
Lugol's iodine
total thyroidectomy
url http://www.ijem.in/article.asp?issn=2230-8210;year=2018;volume=22;issue=3;spage=392;epage=396;aulast=Nair
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AT mishajcbabu preoperativepreparationofhyperthyroidismforthyroidectomyroleofsupersaturatediodineandlithiumcarbonate
AT rijumenon preoperativepreparationofhyperthyroidismforthyroidectomyroleofsupersaturatediodineandlithiumcarbonate
AT pradeepjacob preoperativepreparationofhyperthyroidismforthyroidectomyroleofsupersaturatediodineandlithiumcarbonate