HBV markers in haemodialysis Brazilian patients: a prospective 12-month follow-up
The aim of this study was to determine the prevalence and the incidence of hepatitis B virus (HBV) among haemodialysis (HD) subjects and to evaluate whether testing for serological markers at the time of admission is suitable for HBV screening in this population. One hundred twenty-three patients be...
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
2010-02-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000100017 |
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| author | Regina Célia Moreira Marta Mitiko Deguti Marcilio Figueiredo Lemos Cláudia Patara Saraceni Isabel Takano Oba Angela Maria Miranda Spina Alessandra Stilhano Nascimento-Lima Jorge Fares Raymundo Soares Azevedo Michele Soares Gomes-Gouvêa Flair José Carrilho João Renato Rebello Pinho |
| author_facet | Regina Célia Moreira Marta Mitiko Deguti Marcilio Figueiredo Lemos Cláudia Patara Saraceni Isabel Takano Oba Angela Maria Miranda Spina Alessandra Stilhano Nascimento-Lima Jorge Fares Raymundo Soares Azevedo Michele Soares Gomes-Gouvêa Flair José Carrilho João Renato Rebello Pinho |
| author_sort | Regina Célia Moreira |
| collection | DOAJ |
| description | The aim of this study was to determine the prevalence and the incidence of hepatitis B virus (HBV) among haemodialysis (HD) subjects and to evaluate whether testing for serological markers at the time of admission is suitable for HBV screening in this population. One hundred twenty-three patients belonging to two HD centres from São Paulo, Brazil, were tested prospectively. HBV DNA was detected by polymerase chain reaction (PCR) in each of the prospective subjects (n = 123) during one year. Additionally, all samples (n = 1,476) were analysed for HBV serological markers. The prevalence of hepatitis B core antibody (anti-HBc), hepatitis B surface antigen (HBsAg) and HBV DNA were 34.1%, 15.4% and 8.1%, respectively, while the incidence was null. Fluctuation in HBV serology was observed in one patient. Only 37.8% (17/45) of cases responded to the HBV vaccine. Our results suggest that employing more than one HBV marker and repeated follow-up evaluations may improve HBV screening in HD units. |
| first_indexed | 2024-03-12T18:05:07Z |
| format | Article |
| id | doaj.art-182e0a82849e49228734027e113ed4f1 |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T18:05:07Z |
| publishDate | 2010-02-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-182e0a82849e49228734027e113ed4f12023-08-02T09:28:36ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80602010-02-01105110710810.1590/S0074-02762010000100017HBV markers in haemodialysis Brazilian patients: a prospective 12-month follow-upRegina Célia MoreiraMarta Mitiko DegutiMarcilio Figueiredo LemosCláudia Patara SaraceniIsabel Takano ObaAngela Maria Miranda SpinaAlessandra Stilhano Nascimento-LimaJorge FaresRaymundo Soares AzevedoMichele Soares Gomes-GouvêaFlair José CarrilhoJoão Renato Rebello PinhoThe aim of this study was to determine the prevalence and the incidence of hepatitis B virus (HBV) among haemodialysis (HD) subjects and to evaluate whether testing for serological markers at the time of admission is suitable for HBV screening in this population. One hundred twenty-three patients belonging to two HD centres from São Paulo, Brazil, were tested prospectively. HBV DNA was detected by polymerase chain reaction (PCR) in each of the prospective subjects (n = 123) during one year. Additionally, all samples (n = 1,476) were analysed for HBV serological markers. The prevalence of hepatitis B core antibody (anti-HBc), hepatitis B surface antigen (HBsAg) and HBV DNA were 34.1%, 15.4% and 8.1%, respectively, while the incidence was null. Fluctuation in HBV serology was observed in one patient. Only 37.8% (17/45) of cases responded to the HBV vaccine. Our results suggest that employing more than one HBV marker and repeated follow-up evaluations may improve HBV screening in HD units.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000100017haemodialysishepatitis Bscreening |
| spellingShingle | Regina Célia Moreira Marta Mitiko Deguti Marcilio Figueiredo Lemos Cláudia Patara Saraceni Isabel Takano Oba Angela Maria Miranda Spina Alessandra Stilhano Nascimento-Lima Jorge Fares Raymundo Soares Azevedo Michele Soares Gomes-Gouvêa Flair José Carrilho João Renato Rebello Pinho HBV markers in haemodialysis Brazilian patients: a prospective 12-month follow-up Memorias do Instituto Oswaldo Cruz haemodialysis hepatitis B screening |
| title | HBV markers in haemodialysis Brazilian patients: a prospective 12-month follow-up |
| title_full | HBV markers in haemodialysis Brazilian patients: a prospective 12-month follow-up |
| title_fullStr | HBV markers in haemodialysis Brazilian patients: a prospective 12-month follow-up |
| title_full_unstemmed | HBV markers in haemodialysis Brazilian patients: a prospective 12-month follow-up |
| title_short | HBV markers in haemodialysis Brazilian patients: a prospective 12-month follow-up |
| title_sort | hbv markers in haemodialysis brazilian patients a prospective 12 month follow up |
| topic | haemodialysis hepatitis B screening |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000100017 |
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