The importance of expert review to clarify ambiguous situations for (Q)SAR predictions under ICH M7

The importance of expert review to clarify ambiguous situations for (Q)SAR predictions under ICH M7

Abstract The use of in silico predictions for the assessment of bacterial mutagenicity under the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) M7 guideline is recommended when two complementary (quantitative) structure-activity relationship...

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Bibliographic Details
Main Authors: Robert S. Foster, Adrian Fowkes, Alex Cayley, Andrew Thresher, Anne-Laure D. Werner, Chris G. Barber, Grace Kocks, Rachael E. Tennant, Richard V. Williams, Steven Kane, Susanne A. Stalford
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Genes and Environment
Subjects:
(Q)SAR
ACEM
Ames
Derek Nexus
ICH M7
In silico
Online Access:http://link.springer.com/article/10.1186/s41021-020-00166-y

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