FGF-1 induces expression of LXRα and production of 25-hydroxycholesterol to upregulate the apoE gene in rat astrocytes

FGF-1 induces expression of LXRα and production of 25-hydroxycholesterol to upregulate the apoE gene in rat astrocytes

Fibroblast growth factor 1 (FGF-1) enhances apolipoprotein E (apoE) expression and apoE-HDL biogenesis in autocrine fashion in astrocytes (Ito, J., Y. Nagayasu, R. Lu, A. Kheirollah, M. Hayashi, and S. Yokoyama. Astrocytes produce and secrete FGF-1, which promotes the production of apoE-HDL in a man...

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Bibliographic Details
Main Authors: Rui Lu, Jinichi Ito, Noriyuki Iwamoto, Tomoko Nishimaki-Mogami, Shinji Yokoyama
Format: Article
Language:English
Published: Elsevier 2009-06-01
Series:Journal of Lipid Research
Subjects:
high density lipoprotein
cholesterol
direct repeat 4
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520308130

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