ATP13A2 modifies mitochondrial localization of overexpressed TOM20 to autolysosomal pathway
Mutations in ATP13A2 cause Kufor-Rakeb Syndrome (KRS), a juvenile form of Parkinson’s Disease (PD). The gene product belongs to a diverse family of ion pumps and mediates polyamine influx from lysosomal lumen. While the biochemical and structural studies highlight its unique mechanics, how PD pathol...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707766/?tool=EBI |
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ATP13A2 modifies mitochondrial localization of overexpressed TOM20 to autolysosomal pathway.
Published 2022-01-01
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