Acute toxicity of praziquantel to fish Danio rerio and planktonic crustacean Daphnia magna

This study evaluated the toxicity of the pyrazino isoquinoline anthelmintic praziquantel (PZQ) to the Danio rerio zebrafish and Daphnia magna water flea. The estimated 24 h and 96 h LC50 of PZQ to the zebrafish was 39.9 mg/l and 30.4 mg/l, respectively. The highest 24 h and 96 h non-lethal concentra...

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Main Authors: E Zuskova, V Piackova, O Valentova, K Zalohova, J Velisek
Format: Article
Language:English
Published: Czech Academy of Agricultural Sciences 2022-11-01
Series:Veterinární Medicína
Subjects:
Online Access:https://vetmed.agriculturejournals.cz/artkey/vet-202211-0004_acute-toxicity-of-praziquantel-to-fish-danio-rerio-and-planktonic-crustacean-daphnia-magna.php
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author E Zuskova
V Piackova
O Valentova
K Zalohova
J Velisek
author_facet E Zuskova
V Piackova
O Valentova
K Zalohova
J Velisek
author_sort E Zuskova
collection DOAJ
description This study evaluated the toxicity of the pyrazino isoquinoline anthelmintic praziquantel (PZQ) to the Danio rerio zebrafish and Daphnia magna water flea. The estimated 24 h and 96 h LC50 of PZQ to the zebrafish was 39.9 mg/l and 30.4 mg/l, respectively. The highest 24 h and 96 h non-lethal concentration (LC0) was 21.7 mg/l and 21.2 mg/l, respectively. The mobility inhibition test of the juvenile Daphnia magna revealed a 48 h EC50 of 42.7 mg/l.
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spelling doaj.art-183bd3acd1934ec0b80efad7ef8a99082023-11-30T19:27:14ZengCzech Academy of Agricultural SciencesVeterinární Medicína0375-84271805-93922022-11-01671157958410.17221/7/2022-VETMEDvet-202211-0004Acute toxicity of praziquantel to fish Danio rerio and planktonic crustacean Daphnia magnaE Zuskova0V Piackova1O Valentova2K Zalohova3J Velisek4South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, Ceske Budejovice, Czech RepublicSouth Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, Ceske Budejovice, Czech RepublicSouth Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, Ceske Budejovice, Czech RepublicSouth Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, Ceske Budejovice, Czech RepublicSouth Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, Ceske Budejovice, Czech RepublicThis study evaluated the toxicity of the pyrazino isoquinoline anthelmintic praziquantel (PZQ) to the Danio rerio zebrafish and Daphnia magna water flea. The estimated 24 h and 96 h LC50 of PZQ to the zebrafish was 39.9 mg/l and 30.4 mg/l, respectively. The highest 24 h and 96 h non-lethal concentration (LC0) was 21.7 mg/l and 21.2 mg/l, respectively. The mobility inhibition test of the juvenile Daphnia magna revealed a 48 h EC50 of 42.7 mg/l.https://vetmed.agriculturejournals.cz/artkey/vet-202211-0004_acute-toxicity-of-praziquantel-to-fish-danio-rerio-and-planktonic-crustacean-daphnia-magna.php96 h lc50antiparasiticbath treatmentwater fleazebrafish
spellingShingle E Zuskova
V Piackova
O Valentova
K Zalohova
J Velisek
Acute toxicity of praziquantel to fish Danio rerio and planktonic crustacean Daphnia magna
Veterinární Medicína
96 h lc50
antiparasitic
bath treatment
water flea
zebrafish
title Acute toxicity of praziquantel to fish Danio rerio and planktonic crustacean Daphnia magna
title_full Acute toxicity of praziquantel to fish Danio rerio and planktonic crustacean Daphnia magna
title_fullStr Acute toxicity of praziquantel to fish Danio rerio and planktonic crustacean Daphnia magna
title_full_unstemmed Acute toxicity of praziquantel to fish Danio rerio and planktonic crustacean Daphnia magna
title_short Acute toxicity of praziquantel to fish Danio rerio and planktonic crustacean Daphnia magna
title_sort acute toxicity of praziquantel to fish danio rerio and planktonic crustacean daphnia magna
topic 96 h lc50
antiparasitic
bath treatment
water flea
zebrafish
url https://vetmed.agriculturejournals.cz/artkey/vet-202211-0004_acute-toxicity-of-praziquantel-to-fish-danio-rerio-and-planktonic-crustacean-daphnia-magna.php
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