Helium-3 and helium-4 acceleration by high power laser pulses for hadron therapy

The laser driven acceleration of ions is considered a promising candidate for an ion source for hadron therapy of oncological diseases. Though proton and carbon ion sources are conventionally used for therapy, other light ions can also be utilized. Whereas carbon ions require 400 MeV per nucleon to...

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Main Authors: S. S. Bulanov, E. Esarey, C. B. Schroeder, W. P. Leemans, S. V. Bulanov, D. Margarone, G. Korn, T. Haberer
Format: Article
Language:English
Published: American Physical Society 2015-06-01
Series:Physical Review Special Topics. Accelerators and Beams
Online Access:http://doi.org/10.1103/PhysRevSTAB.18.061302
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author S. S. Bulanov
E. Esarey
C. B. Schroeder
W. P. Leemans
S. V. Bulanov
D. Margarone
G. Korn
T. Haberer
author_facet S. S. Bulanov
E. Esarey
C. B. Schroeder
W. P. Leemans
S. V. Bulanov
D. Margarone
G. Korn
T. Haberer
author_sort S. S. Bulanov
collection DOAJ
description The laser driven acceleration of ions is considered a promising candidate for an ion source for hadron therapy of oncological diseases. Though proton and carbon ion sources are conventionally used for therapy, other light ions can also be utilized. Whereas carbon ions require 400 MeV per nucleon to reach the same penetration depth as 250 MeV protons, helium ions require only 250 MeV per nucleon, which is the lowest energy per nucleon among the light ions (heavier than protons). This fact along with the larger biological damage to cancer cells achieved by helium ions, than that by protons, makes this species an interesting candidate for the laser driven ion source. Two mechanisms (magnetic vortex acceleration and hole-boring radiation pressure acceleration) of PW-class laser driven ion acceleration from liquid and gaseous helium targets are studied with the goal of producing 250 MeV per nucleon helium ion beams that meet the hadron therapy requirements. We show that He^{3} ions, having almost the same penetration depth as He^{4} with the same energy per nucleon, require less laser power to be accelerated to the required energy for the hadron therapy.
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spelling doaj.art-183c316044c344ce89241242d27ff1462022-12-21T18:31:01ZengAmerican Physical SocietyPhysical Review Special Topics. Accelerators and Beams1098-44022015-06-0118606130210.1103/PhysRevSTAB.18.061302Helium-3 and helium-4 acceleration by high power laser pulses for hadron therapyS. S. BulanovE. EsareyC. B. SchroederW. P. LeemansS. V. BulanovD. MargaroneG. KornT. HabererThe laser driven acceleration of ions is considered a promising candidate for an ion source for hadron therapy of oncological diseases. Though proton and carbon ion sources are conventionally used for therapy, other light ions can also be utilized. Whereas carbon ions require 400 MeV per nucleon to reach the same penetration depth as 250 MeV protons, helium ions require only 250 MeV per nucleon, which is the lowest energy per nucleon among the light ions (heavier than protons). This fact along with the larger biological damage to cancer cells achieved by helium ions, than that by protons, makes this species an interesting candidate for the laser driven ion source. Two mechanisms (magnetic vortex acceleration and hole-boring radiation pressure acceleration) of PW-class laser driven ion acceleration from liquid and gaseous helium targets are studied with the goal of producing 250 MeV per nucleon helium ion beams that meet the hadron therapy requirements. We show that He^{3} ions, having almost the same penetration depth as He^{4} with the same energy per nucleon, require less laser power to be accelerated to the required energy for the hadron therapy.http://doi.org/10.1103/PhysRevSTAB.18.061302
spellingShingle S. S. Bulanov
E. Esarey
C. B. Schroeder
W. P. Leemans
S. V. Bulanov
D. Margarone
G. Korn
T. Haberer
Helium-3 and helium-4 acceleration by high power laser pulses for hadron therapy
Physical Review Special Topics. Accelerators and Beams
title Helium-3 and helium-4 acceleration by high power laser pulses for hadron therapy
title_full Helium-3 and helium-4 acceleration by high power laser pulses for hadron therapy
title_fullStr Helium-3 and helium-4 acceleration by high power laser pulses for hadron therapy
title_full_unstemmed Helium-3 and helium-4 acceleration by high power laser pulses for hadron therapy
title_short Helium-3 and helium-4 acceleration by high power laser pulses for hadron therapy
title_sort helium 3 and helium 4 acceleration by high power laser pulses for hadron therapy
url http://doi.org/10.1103/PhysRevSTAB.18.061302
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