Síndrome de Lemierre con distress respiratorio
Lemierre's syndrome is a clinical triad of acute oropharyngeal infection, secondary local invasion and vein thrombosis often involving the internal jugular vein, along with evidence of systemic septic embolism. Usually affecting otherwise healthy adolescents and young adults, anaerobic Fusobact...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sociedade Galega de Medicina Interna
2021-07-01
|
| Series: | Galicia Clínica |
| Subjects: | |
| Online Access: | https://galiciaclinica.info/publicacion.asp?f=2152 |
| _version_ | 1819154910819647488 |
|---|---|
| author | Miguel Silva Eduarda Pena Margarida Oliveira Daniela Carvalho |
| author_facet | Miguel Silva Eduarda Pena Margarida Oliveira Daniela Carvalho |
| author_sort | Miguel Silva |
| collection | DOAJ |
| description | Lemierre's syndrome is a clinical triad of acute oropharyngeal infection, secondary local invasion and vein thrombosis often involving the internal jugular vein, along with evidence of systemic septic embolism. Usually affecting otherwise healthy adolescents and young adults, anaerobic Fusobacterium spp. are often implicated; other bacterial species are sometimes found. While being a rare disease with a reported 14.4 cases per million person-years, it carries a mortality rate of 5 to 9%. Clinical presentation can be severe owing to septic shock, multiorgan dysfunction, septic embolization and acute respiratory distress syndrome requiring ICU admission. Treatment involves antibiotic therapy with anaerobic coverage and supportive care. Anticoagulation use is controversial and surgical treatment may be needed to control focus of infection. There is few quality evidence available regarding the clinical management of this syndrome. We report a case of Lemierre syndrome caused by Streptococcus hemolyticus group c, complicated with pulmonary septic embolism, necrotizing pneumonia, empyema and acute respiratory distress syndrome with a degree of severity that required the use of extracorporeal membrane oxygenation to support the patient. |
| first_indexed | 2024-12-22T15:28:35Z |
| format | Article |
| id | doaj.art-183f829d665d44e9a8235ecd326d8859 |
| institution | Directory Open Access Journal |
| issn | 0304-4866 1989-3922 |
| language | English |
| last_indexed | 2024-12-22T15:28:35Z |
| publishDate | 2021-07-01 |
| publisher | Sociedade Galega de Medicina Interna |
| record_format | Article |
| series | Galicia Clínica |
| spelling | doaj.art-183f829d665d44e9a8235ecd326d88592022-12-21T18:21:26ZengSociedade Galega de Medicina InternaGalicia Clínica0304-48661989-39222021-07-01822969810.22546/61/21522152Síndrome de Lemierre con distress respiratorioMiguel Silva0Eduarda Pena1Margarida Oliveira2Daniela Carvalho3Hospital Pedro HispanoHospital Pedro HispanoHospital Pedro HispanoHospital Pedro HispanoLemierre's syndrome is a clinical triad of acute oropharyngeal infection, secondary local invasion and vein thrombosis often involving the internal jugular vein, along with evidence of systemic septic embolism. Usually affecting otherwise healthy adolescents and young adults, anaerobic Fusobacterium spp. are often implicated; other bacterial species are sometimes found. While being a rare disease with a reported 14.4 cases per million person-years, it carries a mortality rate of 5 to 9%. Clinical presentation can be severe owing to septic shock, multiorgan dysfunction, septic embolization and acute respiratory distress syndrome requiring ICU admission. Treatment involves antibiotic therapy with anaerobic coverage and supportive care. Anticoagulation use is controversial and surgical treatment may be needed to control focus of infection. There is few quality evidence available regarding the clinical management of this syndrome. We report a case of Lemierre syndrome caused by Streptococcus hemolyticus group c, complicated with pulmonary septic embolism, necrotizing pneumonia, empyema and acute respiratory distress syndrome with a degree of severity that required the use of extracorporeal membrane oxygenation to support the patient.https://galiciaclinica.info/publicacion.asp?f=2152síndrome de lemierreestreptococofusobacteriumsíndrome de dificultad respiratoriaadultooxigenación por membrana extracorpórea |
| spellingShingle | Miguel Silva Eduarda Pena Margarida Oliveira Daniela Carvalho Síndrome de Lemierre con distress respiratorio Galicia Clínica síndrome de lemierre estreptococo fusobacterium síndrome de dificultad respiratoria adulto oxigenación por membrana extracorpórea |
| title | Síndrome de Lemierre con distress respiratorio |
| title_full | Síndrome de Lemierre con distress respiratorio |
| title_fullStr | Síndrome de Lemierre con distress respiratorio |
| title_full_unstemmed | Síndrome de Lemierre con distress respiratorio |
| title_short | Síndrome de Lemierre con distress respiratorio |
| title_sort | sindrome de lemierre con distress respiratorio |
| topic | síndrome de lemierre estreptococo fusobacterium síndrome de dificultad respiratoria adulto oxigenación por membrana extracorpórea |
| url | https://galiciaclinica.info/publicacion.asp?f=2152 |
| work_keys_str_mv | AT miguelsilva sindromedelemierrecondistressrespiratorio AT eduardapena sindromedelemierrecondistressrespiratorio AT margaridaoliveira sindromedelemierrecondistressrespiratorio AT danielacarvalho sindromedelemierrecondistressrespiratorio |