Laryngeal mask airway reduces incidence of post-operative sore throat after thyroid surgery compared with endotracheal tube: a single-blinded randomized controlled trial

Abstract Background Sore throat is a remarkable complication after thyroid surgery with endotracheal tube (ETT). Many studies revealed that laryngeal mask airway (LMA) might reduce the incidence and severity of postoperative sore throat. However, little is known about the use of a flexible reinforce...

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Main Authors: Yahong Gong, Xiaohan Xu, Jin Wang, Lu Che, Weijia Wang, Jie Yi
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Anesthesiology
Subjects:
Online Access:https://doi.org/10.1186/s12871-020-0932-2
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author Yahong Gong
Xiaohan Xu
Jin Wang
Lu Che
Weijia Wang
Jie Yi
author_facet Yahong Gong
Xiaohan Xu
Jin Wang
Lu Che
Weijia Wang
Jie Yi
author_sort Yahong Gong
collection DOAJ
description Abstract Background Sore throat is a remarkable complication after thyroid surgery with endotracheal tube (ETT). Many studies revealed that laryngeal mask airway (LMA) might reduce the incidence and severity of postoperative sore throat. However, little is known about the use of a flexible reinforced LMA (FLMA) in thyroid surgery. The purpose of this study was to explore the potential benefits of FLMA compared with ETT on postoperative sore throat. Methods In this prospective, single-blinded, randomized, controlled trial, ninety-six patients aged 20–80 years, scheduled for elective radical thyroidectomy under general anesthesia were enrolled. They were randomly divided into ETT group and FLMA group. All the included patients received total intravenous anesthesia (with propofol, fentanyl and rocuronium) and controlled mechanical ventilation during the surgery. Cuff pressure of ETT and FLMA were strictly controlled. Incidence and severity of postoperative sore throat, numbness and hoarseness at 1, 24, and 48 h after surgery was evaluated and compared between the two groups. Incidence and severity of buckling during extubation and the hemodynamic profile during intubation were also recorded and compared. Results The incidence of sore throat and hoarseness was significantly lower in FLMA group than those in ETT group at 1 h, 24 h and 48 h postoperatively, as well as the severity of sore throat. Compared to ETT group, there was a significantly lower incidence of buckling during extubation and less fluctuation of HR and BP at 1 min and 3 min after intubation in FLMA group. Conclusions Patients undergoing thyroid surgery with FLMA had less postoperative laryngopharyngeal symptoms when compared with ETT. The use of FLMA also achieved less buckling during extubation and better hemodynamic profiles during intubation. Trial registration The research was registered in Chinese Clinical Trial Registry (ChiCTR-IOR-15006602) on May 23th, 2015.
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spelling doaj.art-184123ad0e4c4587af2b1081472e2a7d2022-12-22T03:14:51ZengBMCBMC Anesthesiology1471-22532020-01-012011710.1186/s12871-020-0932-2Laryngeal mask airway reduces incidence of post-operative sore throat after thyroid surgery compared with endotracheal tube: a single-blinded randomized controlled trialYahong Gong0Xiaohan Xu1Jin Wang2Lu Che3Weijia Wang4Jie Yi5Department of Anesthesiology, Peking Union Medical College Hospital (PUMCH)Department of Anesthesiology, Peking Union Medical College Hospital (PUMCH)Department of Anesthesiology, Peking Union Medical College Hospital (PUMCH)Department of Anesthesiology, Peking Union Medical College Hospital (PUMCH)Department of Anesthesiology, Peking Union Medical College Hospital (PUMCH)Department of Anesthesiology, Peking Union Medical College Hospital (PUMCH)Abstract Background Sore throat is a remarkable complication after thyroid surgery with endotracheal tube (ETT). Many studies revealed that laryngeal mask airway (LMA) might reduce the incidence and severity of postoperative sore throat. However, little is known about the use of a flexible reinforced LMA (FLMA) in thyroid surgery. The purpose of this study was to explore the potential benefits of FLMA compared with ETT on postoperative sore throat. Methods In this prospective, single-blinded, randomized, controlled trial, ninety-six patients aged 20–80 years, scheduled for elective radical thyroidectomy under general anesthesia were enrolled. They were randomly divided into ETT group and FLMA group. All the included patients received total intravenous anesthesia (with propofol, fentanyl and rocuronium) and controlled mechanical ventilation during the surgery. Cuff pressure of ETT and FLMA were strictly controlled. Incidence and severity of postoperative sore throat, numbness and hoarseness at 1, 24, and 48 h after surgery was evaluated and compared between the two groups. Incidence and severity of buckling during extubation and the hemodynamic profile during intubation were also recorded and compared. Results The incidence of sore throat and hoarseness was significantly lower in FLMA group than those in ETT group at 1 h, 24 h and 48 h postoperatively, as well as the severity of sore throat. Compared to ETT group, there was a significantly lower incidence of buckling during extubation and less fluctuation of HR and BP at 1 min and 3 min after intubation in FLMA group. Conclusions Patients undergoing thyroid surgery with FLMA had less postoperative laryngopharyngeal symptoms when compared with ETT. The use of FLMA also achieved less buckling during extubation and better hemodynamic profiles during intubation. Trial registration The research was registered in Chinese Clinical Trial Registry (ChiCTR-IOR-15006602) on May 23th, 2015.https://doi.org/10.1186/s12871-020-0932-2Sore throatThyroid surgeryPostoperativeEndotracheal tubeFlexible laryngeal mask airway
spellingShingle Yahong Gong
Xiaohan Xu
Jin Wang
Lu Che
Weijia Wang
Jie Yi
Laryngeal mask airway reduces incidence of post-operative sore throat after thyroid surgery compared with endotracheal tube: a single-blinded randomized controlled trial
BMC Anesthesiology
Sore throat
Thyroid surgery
Postoperative
Endotracheal tube
Flexible laryngeal mask airway
title Laryngeal mask airway reduces incidence of post-operative sore throat after thyroid surgery compared with endotracheal tube: a single-blinded randomized controlled trial
title_full Laryngeal mask airway reduces incidence of post-operative sore throat after thyroid surgery compared with endotracheal tube: a single-blinded randomized controlled trial
title_fullStr Laryngeal mask airway reduces incidence of post-operative sore throat after thyroid surgery compared with endotracheal tube: a single-blinded randomized controlled trial
title_full_unstemmed Laryngeal mask airway reduces incidence of post-operative sore throat after thyroid surgery compared with endotracheal tube: a single-blinded randomized controlled trial
title_short Laryngeal mask airway reduces incidence of post-operative sore throat after thyroid surgery compared with endotracheal tube: a single-blinded randomized controlled trial
title_sort laryngeal mask airway reduces incidence of post operative sore throat after thyroid surgery compared with endotracheal tube a single blinded randomized controlled trial
topic Sore throat
Thyroid surgery
Postoperative
Endotracheal tube
Flexible laryngeal mask airway
url https://doi.org/10.1186/s12871-020-0932-2
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