Evaluation of the safety and acute toxicity of strains of the medicinal Schizophyllum commune fr. fungus

In this article, the safety grading of local strains JE4, JE5 and JE6 of the medicinal fungus S. commune and the study of the effect of acute toxicity in laboratory conditions are analyzed. The mycelial liquid of the strains was given to white mice in the same amount in the mouth, vein, and abdomina...

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Main Authors: Sherqulova Jamila, Eshonkulov Erkin, Qo‘ziboev Xumoyun
Format: Article
Language:English
Published: EDP Sciences 2024-01-01
Series:BIO Web of Conferences
Online Access:https://www.bio-conferences.org/articles/bioconf/pdf/2024/14/bioconf_cibta-iii-2024_01004.pdf
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author Sherqulova Jamila
Eshonkulov Erkin
Qo‘ziboev Xumoyun
author_facet Sherqulova Jamila
Eshonkulov Erkin
Qo‘ziboev Xumoyun
author_sort Sherqulova Jamila
collection DOAJ
description In this article, the safety grading of local strains JE4, JE5 and JE6 of the medicinal fungus S. commune and the study of the effect of acute toxicity in laboratory conditions are analyzed. The mycelial liquid of the strains was given to white mice in the same amount in the mouth, vein, and abdominal cavity. Experimental tasts were observed for 14 days. Permanent signs of dangerous toxicity in animals: changes in the color of the skin, fur, eyes and mucous membranes, activity towards food, behavior, changes in height, movement, sleep, tremors, seizures, salivation cases of separation, diarrhea and death were monitored. It is noted that the strains of Schizophyllum commune are harmless and not acutely toxic.
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spelling doaj.art-1841c619bfef4f6caead951a256ab72f2024-03-29T08:28:08ZengEDP SciencesBIO Web of Conferences2117-44582024-01-01950100410.1051/bioconf/20249501004bioconf_cibta-iii-2024_01004Evaluation of the safety and acute toxicity of strains of the medicinal Schizophyllum commune fr. fungusSherqulova Jamila0Eshonkulov Erkin1Qo‘ziboev Xumoyun2Karshi State UniverstyKarshi State UniverstyKarshi State UniverstyIn this article, the safety grading of local strains JE4, JE5 and JE6 of the medicinal fungus S. commune and the study of the effect of acute toxicity in laboratory conditions are analyzed. The mycelial liquid of the strains was given to white mice in the same amount in the mouth, vein, and abdominal cavity. Experimental tasts were observed for 14 days. Permanent signs of dangerous toxicity in animals: changes in the color of the skin, fur, eyes and mucous membranes, activity towards food, behavior, changes in height, movement, sleep, tremors, seizures, salivation cases of separation, diarrhea and death were monitored. It is noted that the strains of Schizophyllum commune are harmless and not acutely toxic.https://www.bio-conferences.org/articles/bioconf/pdf/2024/14/bioconf_cibta-iii-2024_01004.pdf
spellingShingle Sherqulova Jamila
Eshonkulov Erkin
Qo‘ziboev Xumoyun
Evaluation of the safety and acute toxicity of strains of the medicinal Schizophyllum commune fr. fungus
BIO Web of Conferences
title Evaluation of the safety and acute toxicity of strains of the medicinal Schizophyllum commune fr. fungus
title_full Evaluation of the safety and acute toxicity of strains of the medicinal Schizophyllum commune fr. fungus
title_fullStr Evaluation of the safety and acute toxicity of strains of the medicinal Schizophyllum commune fr. fungus
title_full_unstemmed Evaluation of the safety and acute toxicity of strains of the medicinal Schizophyllum commune fr. fungus
title_short Evaluation of the safety and acute toxicity of strains of the medicinal Schizophyllum commune fr. fungus
title_sort evaluation of the safety and acute toxicity of strains of the medicinal schizophyllum commune fr fungus
url https://www.bio-conferences.org/articles/bioconf/pdf/2024/14/bioconf_cibta-iii-2024_01004.pdf
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