Optimization of extrusion based ceramic 3D printing process for complex bony designs

In this study presents materials and design optimization of clinically approved hydroxyapatite (HA) using extrusion based 3D printing process. The effect of various printing parameters including print speed, extrusion pressure, accuracy and infill density to produce defined porous structures is esta...

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Main Authors: Uday Kiran Roopavath, Sara Malferrari, Annemieke Van Haver, Frederik Verstreken, Subha Narayan Rath, Deepak M. Kalaskar
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Materials & Design
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127518308608
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author Uday Kiran Roopavath
Sara Malferrari
Annemieke Van Haver
Frederik Verstreken
Subha Narayan Rath
Deepak M. Kalaskar
author_facet Uday Kiran Roopavath
Sara Malferrari
Annemieke Van Haver
Frederik Verstreken
Subha Narayan Rath
Deepak M. Kalaskar
author_sort Uday Kiran Roopavath
collection DOAJ
description In this study presents materials and design optimization of clinically approved hydroxyapatite (HA) using extrusion based 3D printing process. The effect of various printing parameters including print speed, extrusion pressure, accuracy and infill density to produce defined porous structures is established using various techniques. Particularly Scanning Electron Microscopy, Micro Computed Tomography have been employed to study internal and external accuracy. Mechanical testing was employed to study the effect of porosity on compressive properties of 3D printed structures.This study shows that, the infill density and shrinkage of 3D printed HA scaffolds post sintering have a linear relationship. Porosity and mechanical strength of 3D printed scaffolds depend on the infill density of the designed CAD file. Tailoring infill density also helps in altering mechanical properties in a predictable manner. Finally, a case study on hydroxyapatite printing of a patient specific bone graft demonstrates the ability of this material and technique to print complex porous structures created on CT-based anatomical bone models and pre-operative 3D planning, providing further promise for custom implant development for complex bony designs. Keywords: 3D printing, Hydroxyapatite, Patient specific bone printing, Bone graft, Radial fracture
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spelling doaj.art-1842239e10af4c258a323084e32cafcf2022-12-21T22:25:32ZengElsevierMaterials & Design0264-12752019-01-01162263270Optimization of extrusion based ceramic 3D printing process for complex bony designsUday Kiran Roopavath0Sara Malferrari1Annemieke Van Haver2Frederik Verstreken3Subha Narayan Rath4Deepak M. Kalaskar5Institute of Musculoskeletal sciences (IOMS), UCL Division of Surgery and Interventional Science, Royal National Orthopaedic Hospital-NHS Trust, HA7 4LP, United Kingdom of Great Britain and Northern Ireland; Department of Biomedical Engineering, Indian Institute of Technology Hyderabad, Kandi, Medak-502285, Telangana, IndiaInstitute of Musculoskeletal sciences (IOMS), UCL Division of Surgery and Interventional Science, Royal National Orthopaedic Hospital-NHS Trust, HA7 4LP, United Kingdom of Great Britain and Northern IrelandMonica Hospital, Monica Orthopedic Research (MORE) Institute & University Hospital Antwerp, BelgiumMonica Hospital, Monica Orthopedic Research (MORE) Institute & University Hospital Antwerp, BelgiumDepartment of Biomedical Engineering, Indian Institute of Technology Hyderabad, Kandi, Medak-502285, Telangana, IndiaInstitute of Musculoskeletal sciences (IOMS), UCL Division of Surgery and Interventional Science, Royal National Orthopaedic Hospital-NHS Trust, HA7 4LP, United Kingdom of Great Britain and Northern Ireland; Corresponding author.In this study presents materials and design optimization of clinically approved hydroxyapatite (HA) using extrusion based 3D printing process. The effect of various printing parameters including print speed, extrusion pressure, accuracy and infill density to produce defined porous structures is established using various techniques. Particularly Scanning Electron Microscopy, Micro Computed Tomography have been employed to study internal and external accuracy. Mechanical testing was employed to study the effect of porosity on compressive properties of 3D printed structures.This study shows that, the infill density and shrinkage of 3D printed HA scaffolds post sintering have a linear relationship. Porosity and mechanical strength of 3D printed scaffolds depend on the infill density of the designed CAD file. Tailoring infill density also helps in altering mechanical properties in a predictable manner. Finally, a case study on hydroxyapatite printing of a patient specific bone graft demonstrates the ability of this material and technique to print complex porous structures created on CT-based anatomical bone models and pre-operative 3D planning, providing further promise for custom implant development for complex bony designs. Keywords: 3D printing, Hydroxyapatite, Patient specific bone printing, Bone graft, Radial fracturehttp://www.sciencedirect.com/science/article/pii/S0264127518308608
spellingShingle Uday Kiran Roopavath
Sara Malferrari
Annemieke Van Haver
Frederik Verstreken
Subha Narayan Rath
Deepak M. Kalaskar
Optimization of extrusion based ceramic 3D printing process for complex bony designs
Materials & Design
title Optimization of extrusion based ceramic 3D printing process for complex bony designs
title_full Optimization of extrusion based ceramic 3D printing process for complex bony designs
title_fullStr Optimization of extrusion based ceramic 3D printing process for complex bony designs
title_full_unstemmed Optimization of extrusion based ceramic 3D printing process for complex bony designs
title_short Optimization of extrusion based ceramic 3D printing process for complex bony designs
title_sort optimization of extrusion based ceramic 3d printing process for complex bony designs
url http://www.sciencedirect.com/science/article/pii/S0264127518308608
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