Characterization of the Roles of Vimentin in Regulating the Proliferation and Migration of HSCs during Hepatic Fibrogenesis

Characterization of the Roles of Vimentin in Regulating the Proliferation and Migration of HSCs during Hepatic Fibrogenesis

The activation of hepatic stellate cells (HSCs) manifested as proliferation and migration is the pivotal event involved in liver fibrogenesis. The vimentin network, an intermediate filament (IF) system, is one of the critical cascades by which the cell morphology, growth, and motility are modulated....

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Bibliographic Details
Main Authors: Pei-Wen Wang, Tung-Ho Wu, Tung-Yi Lin, Mu-Hong Chen, Chau-Ting Yeh, Tai-Long Pan
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cells
Subjects:
hepatic stellate cells
hepatic fibrosis
vimentin
rho
erk
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Online Access:https://www.mdpi.com/2073-4409/8/10/1184

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