Pan-Cancer Bioinformatics Analysis of Gene UBE2C

Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a gene that encodes protein. Disorders associated with UBE2C include methotrexate-related lymphatic hyperplasia and complement component 7 deficiency. The encoded protein is necessary for the destruction of mitotic cell cyclins and cell cycle progression,...

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Main Authors: Lin Yuan, Zhenyu Yang, Jing Zhao, Tao Sun, Chunyu Hu, Zhen Shen, Guanying Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.893358/full
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author Lin Yuan
Zhenyu Yang
Jing Zhao
Tao Sun
Chunyu Hu
Zhen Shen
Guanying Yu
author_facet Lin Yuan
Zhenyu Yang
Jing Zhao
Tao Sun
Chunyu Hu
Zhen Shen
Guanying Yu
author_sort Lin Yuan
collection DOAJ
description Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a gene that encodes protein. Disorders associated with UBE2C include methotrexate-related lymphatic hyperplasia and complement component 7 deficiency. The encoded protein is necessary for the destruction of mitotic cell cyclins and cell cycle progression, and may be involved in cancer progression. In this paper, on the basis of public databases, we study the expression differential mechanism of gene expression of UBE2C in various tumors and the performance of prognosis, clinical features, immunity, methylation, etc.
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spelling doaj.art-1848496a884f4194a6c96c88ca02a11d2022-12-22T02:10:36ZengFrontiers Media S.A.Frontiers in Genetics1664-80212022-04-011310.3389/fgene.2022.893358893358Pan-Cancer Bioinformatics Analysis of Gene UBE2CLin Yuan0Zhenyu Yang1Jing Zhao2Tao Sun3Chunyu Hu4Zhen Shen5Guanying Yu6School of Computer Science and Technology, Qilu University of Technology (Shandong Academy of Sciences), Jinan, ChinaSchool of Computer Science and Technology, Qilu University of Technology (Shandong Academy of Sciences), Jinan, ChinaSchool of Computer Science and Technology, Qilu University of Technology (Shandong Academy of Sciences), Jinan, ChinaSchool of Computer Science and Technology, Qilu University of Technology (Shandong Academy of Sciences), Jinan, ChinaSchool of Computer Science and Technology, Qilu University of Technology (Shandong Academy of Sciences), Jinan, ChinaSchool of Computer and Software, Nanyang Institute of Technology, Nanyang, ChinaDepartment of Gastrointestinal Surgery, Central Hospital Affiliated to Shandong First Medical University, Jinan, ChinaUbiquitin-Conjugating Enzyme E2 C (UBE2C) is a gene that encodes protein. Disorders associated with UBE2C include methotrexate-related lymphatic hyperplasia and complement component 7 deficiency. The encoded protein is necessary for the destruction of mitotic cell cyclins and cell cycle progression, and may be involved in cancer progression. In this paper, on the basis of public databases, we study the expression differential mechanism of gene expression of UBE2C in various tumors and the performance of prognosis, clinical features, immunity, methylation, etc.https://www.frontiersin.org/articles/10.3389/fgene.2022.893358/fullgene Expressionpan-cancerGSE dataprognostic analysisTCGAimmune infiltration
spellingShingle Lin Yuan
Zhenyu Yang
Jing Zhao
Tao Sun
Chunyu Hu
Zhen Shen
Guanying Yu
Pan-Cancer Bioinformatics Analysis of Gene UBE2C
Frontiers in Genetics
gene Expression
pan-cancer
GSE data
prognostic analysis
TCGA
immune infiltration
title Pan-Cancer Bioinformatics Analysis of Gene UBE2C
title_full Pan-Cancer Bioinformatics Analysis of Gene UBE2C
title_fullStr Pan-Cancer Bioinformatics Analysis of Gene UBE2C
title_full_unstemmed Pan-Cancer Bioinformatics Analysis of Gene UBE2C
title_short Pan-Cancer Bioinformatics Analysis of Gene UBE2C
title_sort pan cancer bioinformatics analysis of gene ube2c
topic gene Expression
pan-cancer
GSE data
prognostic analysis
TCGA
immune infiltration
url https://www.frontiersin.org/articles/10.3389/fgene.2022.893358/full
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