Chronic obstructive pulmonary disease and cardiovascular co-morbidities
BACKGROUND Chronic Obstructive Pulmonary Disease (COPD) is the fourth largest cause of death worldwide. However, most patients with COPD die from cardiovascular causes (CVD). COPD is an independent risk factor for CVD and a predictor of long-term mortality. There is a high prevalence of traditional...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2013-05-01
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| Series: | Italian Journal of Medicine |
| Subjects: | |
| Online Access: | http://www.italjmed.org/index.php/ijm/article/view/305 |
| _version_ | 1797426232079417344 |
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| author | Domenico Panuccio Massimo Giusti |
| author_facet | Domenico Panuccio Massimo Giusti |
| author_sort | Domenico Panuccio |
| collection | DOAJ |
| description | BACKGROUND Chronic Obstructive Pulmonary Disease (COPD) is the fourth largest cause of death worldwide. However, most patients with COPD die from cardiovascular causes (CVD). COPD is an independent risk factor for CVD and a predictor of long-term mortality. There is a high prevalence of traditional risk factors in this patient group, including smoking, sedentary behaviour and low socio-economic class. COPD is now recognized to having both local lung and systemic effects. The mechanism of such systemic effects is not completely known, but it is supposed to be related to enhanced systemic inflammation and to oxidative stress, both implicated in the pathogenesis of atherosclerotic process. <br />CONCLUSIONS COPD is frequently associated with congestive heart failure (CHF). It is also a confounding factor for the diagnosis of CHF. In fact, some studies demonstrate that about 20% of patients diagnosed with COPD had also or only CHF. Patients with CHF and associated COPD have less frequently β-blockers prescription than CHF patients without COPD. COPD is a heavy negative prognostic factor for CHF hospitalization and mortality. Pulmonary Embolism (PE) in patients with COPD is generally underdiagnosed, and this last disease is a risk factor for a complicated course of PE, with increased mortality. |
| first_indexed | 2024-03-09T08:27:18Z |
| format | Article |
| id | doaj.art-1849e93b80904e61a4268080c5d3900c |
| institution | Directory Open Access Journal |
| issn | 1877-9344 1877-9352 |
| language | English |
| last_indexed | 2024-03-09T08:27:18Z |
| publishDate | 2013-05-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Italian Journal of Medicine |
| spelling | doaj.art-1849e93b80904e61a4268080c5d3900c2023-12-02T20:59:57ZengPAGEPress PublicationsItalian Journal of Medicine1877-93441877-93522013-05-0123424610.4081/itjm.2008.3.42259Chronic obstructive pulmonary disease and cardiovascular co-morbiditiesDomenico PanuccioMassimo GiustiBACKGROUND Chronic Obstructive Pulmonary Disease (COPD) is the fourth largest cause of death worldwide. However, most patients with COPD die from cardiovascular causes (CVD). COPD is an independent risk factor for CVD and a predictor of long-term mortality. There is a high prevalence of traditional risk factors in this patient group, including smoking, sedentary behaviour and low socio-economic class. COPD is now recognized to having both local lung and systemic effects. The mechanism of such systemic effects is not completely known, but it is supposed to be related to enhanced systemic inflammation and to oxidative stress, both implicated in the pathogenesis of atherosclerotic process. <br />CONCLUSIONS COPD is frequently associated with congestive heart failure (CHF). It is also a confounding factor for the diagnosis of CHF. In fact, some studies demonstrate that about 20% of patients diagnosed with COPD had also or only CHF. Patients with CHF and associated COPD have less frequently β-blockers prescription than CHF patients without COPD. COPD is a heavy negative prognostic factor for CHF hospitalization and mortality. Pulmonary Embolism (PE) in patients with COPD is generally underdiagnosed, and this last disease is a risk factor for a complicated course of PE, with increased mortality.http://www.italjmed.org/index.php/ijm/article/view/305COPDCardiovascular diseaseHeart failurePulmonary embolism. |
| spellingShingle | Domenico Panuccio Massimo Giusti Chronic obstructive pulmonary disease and cardiovascular co-morbidities Italian Journal of Medicine COPD Cardiovascular disease Heart failure Pulmonary embolism. |
| title | Chronic obstructive pulmonary disease and cardiovascular co-morbidities |
| title_full | Chronic obstructive pulmonary disease and cardiovascular co-morbidities |
| title_fullStr | Chronic obstructive pulmonary disease and cardiovascular co-morbidities |
| title_full_unstemmed | Chronic obstructive pulmonary disease and cardiovascular co-morbidities |
| title_short | Chronic obstructive pulmonary disease and cardiovascular co-morbidities |
| title_sort | chronic obstructive pulmonary disease and cardiovascular co morbidities |
| topic | COPD Cardiovascular disease Heart failure Pulmonary embolism. |
| url | http://www.italjmed.org/index.php/ijm/article/view/305 |
| work_keys_str_mv | AT domenicopanuccio chronicobstructivepulmonarydiseaseandcardiovascularcomorbidities AT massimogiusti chronicobstructivepulmonarydiseaseandcardiovascularcomorbidities |