Interactions of carbon nanotubes and fullerenes with the immune system of the skin and the possible implications related to cutaneous nanotoxicity
The understanding of the interaction of carbon nanotubes and fullerenes with the constituents of the skin, especially the skin immune unit, is relevant to the determina-tion of toxicological endpoints. A systematic review was done focused on such aspects. Considerable part of the found references co...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Fundação Oswaldo Cruz (FIOCRUZ)
2013-11-01
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| Series: | Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia |
| Subjects: | |
| Online Access: | http://www.visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/107/106 |
| _version_ | 1811323499336171520 |
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| author | Ana Luiza Castro Fernandes William Waissmann |
| author_facet | Ana Luiza Castro Fernandes William Waissmann |
| author_sort | Ana Luiza Castro Fernandes |
| collection | DOAJ |
| description | The understanding of the interaction of carbon nanotubes and fullerenes with the constituents of the skin, especially the skin immune unit, is relevant to the determina-tion of toxicological endpoints. A systematic review was done focused on such aspects. Considerable part of the found references concentrated in cytotoxicity and skin per-meation. On a smaller scale, there are articles on immunomodulation and activation of immune cells and other elements. Few of the found studies deal specifically with cutaneous immune response, limiting the related knowledge. The findings suggest that nanomaterials studied may be involved in skin problems such irritant contact dermatitis, anaphylactoid reactions, urticaria, angioedema, and raised the need for performing additional studies to confirm the findings. The standardization of the description and testing of nanomaterials characteristics used in experiments can facilitate comparison of results. |
| first_indexed | 2024-04-13T13:56:15Z |
| format | Article |
| id | doaj.art-184b02f846d1419b8fb88e9cba9065bb |
| institution | Directory Open Access Journal |
| issn | 2317-269X |
| language | English |
| last_indexed | 2024-04-13T13:56:15Z |
| publishDate | 2013-11-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia |
| spelling | doaj.art-184b02f846d1419b8fb88e9cba9065bb2022-12-22T02:44:10ZengFundação Oswaldo Cruz (FIOCRUZ)Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia2317-269X2013-11-01149210310.3395/vd.v1i4.107enInteractions of carbon nanotubes and fullerenes with the immune system of the skin and the possible implications related to cutaneous nanotoxicityAna Luiza Castro Fernandes0William Waissmann1Hospital Federal dos Servidores do Estado do Rio de Janeiro (HFSE-RJ), Rio de Janeiro, RJ, Brasil E-mail: analuizacf@gmail.comEscola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz (ENSP/Fiocruz), Rio de Janeiro, RJ, BrasilThe understanding of the interaction of carbon nanotubes and fullerenes with the constituents of the skin, especially the skin immune unit, is relevant to the determina-tion of toxicological endpoints. A systematic review was done focused on such aspects. Considerable part of the found references concentrated in cytotoxicity and skin per-meation. On a smaller scale, there are articles on immunomodulation and activation of immune cells and other elements. Few of the found studies deal specifically with cutaneous immune response, limiting the related knowledge. The findings suggest that nanomaterials studied may be involved in skin problems such irritant contact dermatitis, anaphylactoid reactions, urticaria, angioedema, and raised the need for performing additional studies to confirm the findings. The standardization of the description and testing of nanomaterials characteristics used in experiments can facilitate comparison of results.http://www.visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/107/106Fullerenes; Carbon Nanotubes; Allergy and Immunology; Skin Diseases |
| spellingShingle | Ana Luiza Castro Fernandes William Waissmann Interactions of carbon nanotubes and fullerenes with the immune system of the skin and the possible implications related to cutaneous nanotoxicity Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia Fullerenes; Carbon Nanotubes; Allergy and Immunology; Skin Diseases |
| title | Interactions of carbon nanotubes and fullerenes with the immune system of the skin and the possible implications related to cutaneous nanotoxicity |
| title_full | Interactions of carbon nanotubes and fullerenes with the immune system of the skin and the possible implications related to cutaneous nanotoxicity |
| title_fullStr | Interactions of carbon nanotubes and fullerenes with the immune system of the skin and the possible implications related to cutaneous nanotoxicity |
| title_full_unstemmed | Interactions of carbon nanotubes and fullerenes with the immune system of the skin and the possible implications related to cutaneous nanotoxicity |
| title_short | Interactions of carbon nanotubes and fullerenes with the immune system of the skin and the possible implications related to cutaneous nanotoxicity |
| title_sort | interactions of carbon nanotubes and fullerenes with the immune system of the skin and the possible implications related to cutaneous nanotoxicity |
| topic | Fullerenes; Carbon Nanotubes; Allergy and Immunology; Skin Diseases |
| url | http://www.visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/107/106 |
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