APC mutation correlated with poor response of immunotherapy in colon cancer

APC mutation correlated with poor response of immunotherapy in colon cancer

Abstract Objective APC (adenomatous polyposis coli) gene mutation is a central initialization in colon cancer tumorigenesis. However, the connection between APC gene mutation and immunotherapy efficacy for colon cancer remains unknown. This study aimed to explore the impact of APC mutation on immuno...

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Bibliographic Details
Main Authors: Bing Li, Guoliang Zhang, Xuejie Xu
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Gastroenterology
Subjects:
APC mutation
colon cancer
Tumor mutation burden
Immunotherapy
Immune cell infiltration
Online Access:https://doi.org/10.1186/s12876-023-02725-3

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