Correlation between Human Boca virus and IL-23in some Iraqi patients with ischemic heart disease
Heart diseases in the Iraqi population are a significant public health concern. Iraq has experienced in the prevalence of heart diseases, including coronary artery disease, heart failure and hypertension. Different researches have shown that human Boca virus (HBoV) may be a risk factor, for some ca...
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| Format: | Article |
| Language: | English |
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Alsalam university college
2024-04-01
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| Series: | Al-SalamJournal for Medical Science |
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| Online Access: | https://journal.alsalam.edu.iq/index.php/ajbms/article/view/244 |
| _version_ | 1827274768411262976 |
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| author | Rafal Hussein Alshate Wisal Salman Abd |
| author_facet | Rafal Hussein Alshate Wisal Salman Abd |
| author_sort | Rafal Hussein Alshate |
| collection | DOAJ |
| description |
Heart diseases in the Iraqi population are a significant public health concern. Iraq has experienced in the prevalence of heart diseases, including coronary artery disease, heart failure and hypertension. Different researches have shown that human Boca virus (HBoV) may be a risk factor, for some cardiac disorders. Hence, goals of resent work is to investigate roles of human Boca virus in ischemia heart disease (IHD) and to investigate roles of serum level of IL-23 in these diseases. 40 heart diseases patients and 40 controls were included. Controls were females (n=30) followed by males (n=10), while patients with IHD were 27 males and 13 females. There were highly significant variations in ages of patients and controls with (p≤0.01). The mean ± SE of age of patients with IHD was 37.90 ±0.75 years, while the mean ± SE of controls was 40.52 ±0.79 years. Lipid profile was measured. There were significant variations between patients' and controls. Also, mean ± SE of HDL was statistically significant between ischemia and control groups (85.28 ±4.31 and 55.10 ±1.23 mg/dl) with p≤0.01, respectively. The serum levels of IgG and IgM were assessed using ELISA. There was no significant variation in mean ± SE of serum level of IgM between ischemia and healthy controls (0.251 ±0.04 and. 0.341 ±0.07 ug/Ml). respectively. There were significant variations in mean ± SE of serum level of IgG between ischemia and controls (0.723 ±0.16 and. 0.076 ±0.004 ug/ml). There were highly significantly differences in Mean ± SE of serum level of 1L-23 between IHD heart diseases (0.407 ±0.073 Pg/mL) and healthy controls (0.0121 ±0.003 pg/mL) with p<0.001, respectively.
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| first_indexed | 2024-04-24T05:53:02Z |
| format | Article |
| id | doaj.art-1851908e72dc4267814abe0175fd494b |
| institution | Directory Open Access Journal |
| issn | 2958-0870 2959-5398 |
| language | English |
| last_indexed | 2025-03-22T06:30:15Z |
| publishDate | 2024-04-01 |
| publisher | Alsalam university college |
| record_format | Article |
| series | Al-SalamJournal for Medical Science |
| spelling | doaj.art-1851908e72dc4267814abe0175fd494b2024-04-25T10:05:44ZengAlsalam university collegeAl-SalamJournal for Medical Science2958-08702959-53982024-04-013210.55145/ajbms.2024.03.02.03Correlation between Human Boca virus and IL-23in some Iraqi patients with ischemic heart diseaseRafal Hussein Alshate0Wisal Salman Abd1Biotechnology Department, College of science, University of Baghdad, Baghdad, Iraq.Assistant Professor of Biotechnology, Department of Biotechnology department, College of science, University of Baghdad, Baghdad, Iraq. Heart diseases in the Iraqi population are a significant public health concern. Iraq has experienced in the prevalence of heart diseases, including coronary artery disease, heart failure and hypertension. Different researches have shown that human Boca virus (HBoV) may be a risk factor, for some cardiac disorders. Hence, goals of resent work is to investigate roles of human Boca virus in ischemia heart disease (IHD) and to investigate roles of serum level of IL-23 in these diseases. 40 heart diseases patients and 40 controls were included. Controls were females (n=30) followed by males (n=10), while patients with IHD were 27 males and 13 females. There were highly significant variations in ages of patients and controls with (p≤0.01). The mean ± SE of age of patients with IHD was 37.90 ±0.75 years, while the mean ± SE of controls was 40.52 ±0.79 years. Lipid profile was measured. There were significant variations between patients' and controls. Also, mean ± SE of HDL was statistically significant between ischemia and control groups (85.28 ±4.31 and 55.10 ±1.23 mg/dl) with p≤0.01, respectively. The serum levels of IgG and IgM were assessed using ELISA. There was no significant variation in mean ± SE of serum level of IgM between ischemia and healthy controls (0.251 ±0.04 and. 0.341 ±0.07 ug/Ml). respectively. There were significant variations in mean ± SE of serum level of IgG between ischemia and controls (0.723 ±0.16 and. 0.076 ±0.004 ug/ml). There were highly significantly differences in Mean ± SE of serum level of 1L-23 between IHD heart diseases (0.407 ±0.073 Pg/mL) and healthy controls (0.0121 ±0.003 pg/mL) with p<0.001, respectively. https://journal.alsalam.edu.iq/index.php/ajbms/article/view/244IL-23IHDHeart diseaseELISA |
| spellingShingle | Rafal Hussein Alshate Wisal Salman Abd Correlation between Human Boca virus and IL-23in some Iraqi patients with ischemic heart disease Al-SalamJournal for Medical Science IL-23 IHD Heart disease ELISA |
| title | Correlation between Human Boca virus and IL-23in some Iraqi patients with ischemic heart disease |
| title_full | Correlation between Human Boca virus and IL-23in some Iraqi patients with ischemic heart disease |
| title_fullStr | Correlation between Human Boca virus and IL-23in some Iraqi patients with ischemic heart disease |
| title_full_unstemmed | Correlation between Human Boca virus and IL-23in some Iraqi patients with ischemic heart disease |
| title_short | Correlation between Human Boca virus and IL-23in some Iraqi patients with ischemic heart disease |
| title_sort | correlation between human boca virus and il 23in some iraqi patients with ischemic heart disease |
| topic | IL-23 IHD Heart disease ELISA |
| url | https://journal.alsalam.edu.iq/index.php/ajbms/article/view/244 |
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