DETERMINATION OF STRUCTURAL-MECHANICAL PROPERTIES OF SOFT DRUGS
The possibility of determining the structural and mechanical properties of ointment and creamy bases, such as the yield point, speed and degree of stress relaxation and thixotropic structure restoration, is described. The proposed method consists in measuring the mechanical stress that occurs when t...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
|
| Series: | Разработка и регистрация лекарственных средств |
| Subjects: | |
| Online Access: | https://www.pharmjournal.ru/jour/article/view/460 |
| Summary: | The possibility of determining the structural and mechanical properties of ointment and creamy bases, such as the yield point, speed and degree of stress relaxation and thixotropic structure restoration, is described. The proposed method consists in measuring the mechanical stress that occurs when the tester is immersed in a consistency mass. The dependence of the mechanical stress measured in the process of relaxation on the logarithm of time is linear, which makes it simple and convenient to determine the structural and mechanical properties of the test samples. |
|---|---|
| ISSN: | 2305-2066 2658-5049 |