Sex differences in cardiovascular risk, lifestyle, and psychological factors in patients with type 2 diabetes: the Fukuoka Diabetes Registry
Abstract Background The excess risk of cardiovascular diseases associated with diabetes is greater in women than in men. The present study aimed to examine sex differences in the control of cardiovascular risk factors, as well as lifestyle and psychological factors, in patients with type 2 diabetes....
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-05-01
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| Series: | Biology of Sex Differences |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13293-023-00517-8 |
| _version_ | 1797818188641075200 |
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| author | Toshiaki Ohkuma Masanori Iwase Hiroki Fujii Takanari Kitazono |
| author_facet | Toshiaki Ohkuma Masanori Iwase Hiroki Fujii Takanari Kitazono |
| author_sort | Toshiaki Ohkuma |
| collection | DOAJ |
| description | Abstract Background The excess risk of cardiovascular diseases associated with diabetes is greater in women than in men. The present study aimed to examine sex differences in the control of cardiovascular risk factors, as well as lifestyle and psychological factors, in patients with type 2 diabetes. Methods A total of 4923 Japanese patients with type 2 diabetes were included in this cross-sectional study. Female/male differences in cardiovascular risk factor levels, and corresponding odds ratios for achieving recommended ranges for preventing cardiovascular diseases and having unhealthy lifestyle and psychological factors were computed by linear and logistic regression models. Results Women were less likely than men to achieve recommended ranges for glycated hemoglobin, low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and obesity-related anthropometric indices such as body mass index and waist circumference, but were more likely than men to be on target for high-density lipoprotein cholesterol and triglycerides. Women were also more likely than men to have an unhealthy lifestyle and psychological factors, including less dietary fiber intake, less leisure-time physical activity, shorter sleep duration, more constipation, and more depressive symptoms. Similar findings were observed when the participants were subgrouped by age (< 65 and ≥ 65 years) and past history of cardiovascular disease. Conclusions We observed significant sex differences for a range of cardiovascular risk factors, as well as lifestyle and psychological factors, suggesting the importance of adopting a sex-specific approach for the daily clinical management of diabetes. |
| first_indexed | 2024-03-13T09:04:26Z |
| format | Article |
| id | doaj.art-1854f6091fe345009f69639ecc82e907 |
| institution | Directory Open Access Journal |
| issn | 2042-6410 |
| language | English |
| last_indexed | 2024-03-13T09:04:26Z |
| publishDate | 2023-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Biology of Sex Differences |
| spelling | doaj.art-1854f6091fe345009f69639ecc82e9072023-05-28T11:06:37ZengBMCBiology of Sex Differences2042-64102023-05-0114111010.1186/s13293-023-00517-8Sex differences in cardiovascular risk, lifestyle, and psychological factors in patients with type 2 diabetes: the Fukuoka Diabetes RegistryToshiaki Ohkuma0Masanori Iwase1Hiroki Fujii2Takanari Kitazono3Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu UniversityDepartment of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu UniversityDepartment of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu UniversityDepartment of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu UniversityAbstract Background The excess risk of cardiovascular diseases associated with diabetes is greater in women than in men. The present study aimed to examine sex differences in the control of cardiovascular risk factors, as well as lifestyle and psychological factors, in patients with type 2 diabetes. Methods A total of 4923 Japanese patients with type 2 diabetes were included in this cross-sectional study. Female/male differences in cardiovascular risk factor levels, and corresponding odds ratios for achieving recommended ranges for preventing cardiovascular diseases and having unhealthy lifestyle and psychological factors were computed by linear and logistic regression models. Results Women were less likely than men to achieve recommended ranges for glycated hemoglobin, low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and obesity-related anthropometric indices such as body mass index and waist circumference, but were more likely than men to be on target for high-density lipoprotein cholesterol and triglycerides. Women were also more likely than men to have an unhealthy lifestyle and psychological factors, including less dietary fiber intake, less leisure-time physical activity, shorter sleep duration, more constipation, and more depressive symptoms. Similar findings were observed when the participants were subgrouped by age (< 65 and ≥ 65 years) and past history of cardiovascular disease. Conclusions We observed significant sex differences for a range of cardiovascular risk factors, as well as lifestyle and psychological factors, suggesting the importance of adopting a sex-specific approach for the daily clinical management of diabetes.https://doi.org/10.1186/s13293-023-00517-8Cardiovascular risk factorDiabetesLifestylePsychosocial factorSex difference |
| spellingShingle | Toshiaki Ohkuma Masanori Iwase Hiroki Fujii Takanari Kitazono Sex differences in cardiovascular risk, lifestyle, and psychological factors in patients with type 2 diabetes: the Fukuoka Diabetes Registry Biology of Sex Differences Cardiovascular risk factor Diabetes Lifestyle Psychosocial factor Sex difference |
| title | Sex differences in cardiovascular risk, lifestyle, and psychological factors in patients with type 2 diabetes: the Fukuoka Diabetes Registry |
| title_full | Sex differences in cardiovascular risk, lifestyle, and psychological factors in patients with type 2 diabetes: the Fukuoka Diabetes Registry |
| title_fullStr | Sex differences in cardiovascular risk, lifestyle, and psychological factors in patients with type 2 diabetes: the Fukuoka Diabetes Registry |
| title_full_unstemmed | Sex differences in cardiovascular risk, lifestyle, and psychological factors in patients with type 2 diabetes: the Fukuoka Diabetes Registry |
| title_short | Sex differences in cardiovascular risk, lifestyle, and psychological factors in patients with type 2 diabetes: the Fukuoka Diabetes Registry |
| title_sort | sex differences in cardiovascular risk lifestyle and psychological factors in patients with type 2 diabetes the fukuoka diabetes registry |
| topic | Cardiovascular risk factor Diabetes Lifestyle Psychosocial factor Sex difference |
| url | https://doi.org/10.1186/s13293-023-00517-8 |
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