Phenolic Compounds from Allium schoenoprasum, Tragopogon pratensis and Rumex acetosa and Their Antiproliferative Effects
Experimental studies have shown that phenolic compounds have antiproliferative and tumour arresting effects. The aim of this original study was to investigate the content of phenolic compounds (PhC) in flowers of Allium schoenoprasum (chive), Tragopogon pratensis (meadow salsify) and Rumex acetosa (...
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| Format: | Article |
| Language: | English |
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MDPI AG
2011-11-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/16/11/9207/ |
| _version_ | 1811326446182858752 |
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| author | Petr Saha Otakar Rop Pavel Valasek Petr Humpolicek Jiri Mlcek Zdenka Kucekova |
| author_facet | Petr Saha Otakar Rop Pavel Valasek Petr Humpolicek Jiri Mlcek Zdenka Kucekova |
| author_sort | Petr Saha |
| collection | DOAJ |
| description | Experimental studies have shown that phenolic compounds have antiproliferative and tumour arresting effects. The aim of this original study was to investigate the content of phenolic compounds (PhC) in flowers of Allium schoenoprasum (chive), Tragopogon pratensis (meadow salsify) and Rumex acetosa (common sorrel) and their effect on proliferation of HaCaT cells. Antiproliferative effects were evaluated in vitro using the following concentrations of phenolic compounds in cultivation medium: 100, 75, 50 and 25 µg/mL. Phenolic composition was also determined by HPLC. The results indicate that even low concentrations of these flowers’ phenolic compounds inhibited cell proliferation significantly and the possible use of the studied herb’s flowers as sources of active phenolic compounds for human nutrition. |
| first_indexed | 2024-04-13T14:50:27Z |
| format | Article |
| id | doaj.art-185beb753fc44a7287aa8cf86be3c58a |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-04-13T14:50:27Z |
| publishDate | 2011-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-185beb753fc44a7287aa8cf86be3c58a2022-12-22T02:42:37ZengMDPI AGMolecules1420-30492011-11-0116119207921710.3390/molecules16119207Phenolic Compounds from Allium schoenoprasum, Tragopogon pratensis and Rumex acetosa and Their Antiproliferative EffectsPetr SahaOtakar RopPavel ValasekPetr HumpolicekJiri MlcekZdenka KucekovaExperimental studies have shown that phenolic compounds have antiproliferative and tumour arresting effects. The aim of this original study was to investigate the content of phenolic compounds (PhC) in flowers of Allium schoenoprasum (chive), Tragopogon pratensis (meadow salsify) and Rumex acetosa (common sorrel) and their effect on proliferation of HaCaT cells. Antiproliferative effects were evaluated in vitro using the following concentrations of phenolic compounds in cultivation medium: 100, 75, 50 and 25 µg/mL. Phenolic composition was also determined by HPLC. The results indicate that even low concentrations of these flowers’ phenolic compounds inhibited cell proliferation significantly and the possible use of the studied herb’s flowers as sources of active phenolic compounds for human nutrition.http://www.mdpi.com/1420-3049/16/11/9207/Allium schoenoprasumTragopogon pratensisRumex acetosaproliferationphenolic compoundsHaCaT |
| spellingShingle | Petr Saha Otakar Rop Pavel Valasek Petr Humpolicek Jiri Mlcek Zdenka Kucekova Phenolic Compounds from Allium schoenoprasum, Tragopogon pratensis and Rumex acetosa and Their Antiproliferative Effects Molecules Allium schoenoprasum Tragopogon pratensis Rumex acetosa proliferation phenolic compounds HaCaT |
| title | Phenolic Compounds from Allium schoenoprasum, Tragopogon pratensis and Rumex acetosa and Their Antiproliferative Effects |
| title_full | Phenolic Compounds from Allium schoenoprasum, Tragopogon pratensis and Rumex acetosa and Their Antiproliferative Effects |
| title_fullStr | Phenolic Compounds from Allium schoenoprasum, Tragopogon pratensis and Rumex acetosa and Their Antiproliferative Effects |
| title_full_unstemmed | Phenolic Compounds from Allium schoenoprasum, Tragopogon pratensis and Rumex acetosa and Their Antiproliferative Effects |
| title_short | Phenolic Compounds from Allium schoenoprasum, Tragopogon pratensis and Rumex acetosa and Their Antiproliferative Effects |
| title_sort | phenolic compounds from allium schoenoprasum tragopogon pratensis and rumex acetosa and their antiproliferative effects |
| topic | Allium schoenoprasum Tragopogon pratensis Rumex acetosa proliferation phenolic compounds HaCaT |
| url | http://www.mdpi.com/1420-3049/16/11/9207/ |
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