Protective role of trametenolic acid B against sevoflurane-induced cognitive impairments by its different regulatory modalities of mir-329-3p in neurons and microglia

Protective role of trametenolic acid B against sevoflurane-induced cognitive impairments by its different regulatory modalities of mir-329-3p in neurons and microglia

Abstract Background Postoperative cognitive dysfunction induced by anesthetics commonly occurs in elderly patients. This study aimed to evaluate the protective role of trametenolic acid B (TAB) in sevoflurane-induced cognitive impairments, and explore the underlying mechanisms. Methods Animal and ce...

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Bibliographic Details
Main Authors: Jun Chen, Shuo Feng, Linyan Li, Shujie Qiu, Yanwu Jin, Yingui Sun
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Molecular Medicine
Subjects:
Postoperative cognitive dysfunction
Trametenolic acid B
Sevoflurane
Neurotoxicity
Neuroinflammation
MicroRNAs
Online Access:https://doi.org/10.1186/s10020-022-00477-6

Internet

https://doi.org/10.1186/s10020-022-00477-6

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