Nanoplasmonic biosensors for precision medicine

Nanoplasmonic biosensors have a huge boost for precision medicine, which allows doctors to better understand diseases at the molecular level and to improve the earlier diagnosis and develop treatment programs. Unlike traditional biosensors, nanoplasmonic biosensors meet the global health industry’s...

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Main Authors: Yiran Xiao, Zongming Zhang, Shi Yin, Xingyi Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2023.1209744/full
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author Yiran Xiao
Zongming Zhang
Shi Yin
Xingyi Ma
Xingyi Ma
Xingyi Ma
author_facet Yiran Xiao
Zongming Zhang
Shi Yin
Xingyi Ma
Xingyi Ma
Xingyi Ma
author_sort Yiran Xiao
collection DOAJ
description Nanoplasmonic biosensors have a huge boost for precision medicine, which allows doctors to better understand diseases at the molecular level and to improve the earlier diagnosis and develop treatment programs. Unlike traditional biosensors, nanoplasmonic biosensors meet the global health industry’s need for low-cost, rapid and portable aspects, while offering multiplexing, high sensitivity and real-time detection. In this review, we describe the common detection schemes used based on localized plasmon resonance (LSPR) and highlight three sensing classes based on LSPR. Then, we present the recent applications of nanoplasmonic in other sensing methods such as isothermal amplification, CRISPR/Cas systems, lab on a chip and enzyme-linked immunosorbent assay. The advantages of nanoplasmonic-based integrated sensing for multiple methods are discussed. Finally, we review the current applications of nanoplasmonic biosensors in precision medicine, such as DNA mutation, vaccine evaluation and drug delivery. The obstacles faced by nanoplasmonic biosensors and the current countermeasures are discussed.
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spelling doaj.art-1861fc060f2d4505bd4b82c88750f8df2023-07-06T16:27:03ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462023-07-011110.3389/fchem.2023.12097441209744Nanoplasmonic biosensors for precision medicineYiran Xiao0Zongming Zhang1Shi Yin2Xingyi Ma3Xingyi Ma4Xingyi Ma5School of Science, Harbin Institute of Technology, Shenzhen, Guangdong, ChinaBiosen International, Jinan, Shandong, ChinaBriteley Institute of Life Sciences, Yantai, Shandong, ChinaSchool of Science, Harbin Institute of Technology, Shenzhen, Guangdong, ChinaBiosen International, Jinan, Shandong, ChinaBriteley Institute of Life Sciences, Yantai, Shandong, ChinaNanoplasmonic biosensors have a huge boost for precision medicine, which allows doctors to better understand diseases at the molecular level and to improve the earlier diagnosis and develop treatment programs. Unlike traditional biosensors, nanoplasmonic biosensors meet the global health industry’s need for low-cost, rapid and portable aspects, while offering multiplexing, high sensitivity and real-time detection. In this review, we describe the common detection schemes used based on localized plasmon resonance (LSPR) and highlight three sensing classes based on LSPR. Then, we present the recent applications of nanoplasmonic in other sensing methods such as isothermal amplification, CRISPR/Cas systems, lab on a chip and enzyme-linked immunosorbent assay. The advantages of nanoplasmonic-based integrated sensing for multiple methods are discussed. Finally, we review the current applications of nanoplasmonic biosensors in precision medicine, such as DNA mutation, vaccine evaluation and drug delivery. The obstacles faced by nanoplasmonic biosensors and the current countermeasures are discussed.https://www.frontiersin.org/articles/10.3389/fchem.2023.1209744/fullnanoplasmonicbiosensorsprecision medicinelocalized surface plasmon resonancesurface-enhanced Raman scatteringlab on a particle
spellingShingle Yiran Xiao
Zongming Zhang
Shi Yin
Xingyi Ma
Xingyi Ma
Xingyi Ma
Nanoplasmonic biosensors for precision medicine
Frontiers in Chemistry
nanoplasmonic
biosensors
precision medicine
localized surface plasmon resonance
surface-enhanced Raman scattering
lab on a particle
title Nanoplasmonic biosensors for precision medicine
title_full Nanoplasmonic biosensors for precision medicine
title_fullStr Nanoplasmonic biosensors for precision medicine
title_full_unstemmed Nanoplasmonic biosensors for precision medicine
title_short Nanoplasmonic biosensors for precision medicine
title_sort nanoplasmonic biosensors for precision medicine
topic nanoplasmonic
biosensors
precision medicine
localized surface plasmon resonance
surface-enhanced Raman scattering
lab on a particle
url https://www.frontiersin.org/articles/10.3389/fchem.2023.1209744/full
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AT xingyima nanoplasmonicbiosensorsforprecisionmedicine
AT xingyima nanoplasmonicbiosensorsforprecisionmedicine
AT xingyima nanoplasmonicbiosensorsforprecisionmedicine