Activation and cytokine profile of monocyte derived dendritic cells in leprosy: in vitro stimulation by sonicated <italic>Mycobacterium leprae</italic> induces decreased level of IL-12p70 in lepromatous leprosy

Activation and cytokine profile of monocyte derived dendritic cells in leprosy: in vitro stimulation by sonicated <italic>Mycobacterium leprae</italic> induces decreased level of IL-12p70 in lepromatous leprosy

<p>Dendritic cells (DCs) play a pivotal role in the connection of innate and adaptive immunity of hosts to mycobacterial infection. Studies on the interaction of monocyte-derived DCs (MO-DCs) using <italic>Mycobacterium leprae</italic> in leprosy patients are rare. The present stud...

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Bibliographic Details
Main Authors: André Flores Braga, Daniela Ferraz Moretto, Patrícia Gigliotti, Mariela Peruchi, Fátima Regina Vilani-Moreno, Ana Paula Campanelli, Ana Carla Pereira Latini, Anand Iyer, Pranab Kumar Das, Vânia Nieto Brito de Souza
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2015-08-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
leprosy
dendritic cells
IL-12p70
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000500655&lng=en&tlng=en

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