Role of Estradiol Hormone in Human Life and Electrochemical Aptasensing of 17β-Estradiol: A Review
Estradiol is known as one of the most potent estrogenic endocrine-disrupting chemicals (EDCs) that may cause various health implications on human growth, metabolism regulation, the reproduction system, and possibly cancers. The detection of these EDCs in our surroundings, such as in foods and bevera...
| Автори: | , , , , |
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| Формат: | Стаття |
| Мова: | English |
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MDPI AG
2022-12-01
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| Серія: | Biosensors |
| Предмети: | |
| Онлайн доступ: | https://www.mdpi.com/2079-6374/12/12/1117 |
| _version_ | 1827641513539010560 |
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| author | P. P. Waifalkar Daegwon Noh Poorva Derashri Sagar Barage Eunsoon Oh |
| author_facet | P. P. Waifalkar Daegwon Noh Poorva Derashri Sagar Barage Eunsoon Oh |
| author_sort | P. P. Waifalkar |
| collection | DOAJ |
| description | Estradiol is known as one of the most potent estrogenic endocrine-disrupting chemicals (EDCs) that may cause various health implications on human growth, metabolism regulation, the reproduction system, and possibly cancers. The detection of these EDCs in our surroundings, such as in foods and beverages, is important to prevent such harmful effects on humans. Aptamers are a promising class of bio-receptors for estradiol detection due to their chemical stability and high affinity. With the development of aptamer technology, electrochemical aptasensing became an important tool for estradiol detection. This review provides detailed information on various technological interventions in electrochemical estradiol detection in solutions and categorized the aptasensing mechanisms, aptamer immobilization strategies, and electrode materials. Moreover, we also discussed the role of estradiol in human physiology and signaling mechanisms. The level of estradiol in circulation is associated with normal and diseased conditions. The aptamer-based electrochemical sensing techniques are powerful and sensitive for estradiol detection. |
| first_indexed | 2024-03-09T17:15:56Z |
| format | Article |
| id | doaj.art-18644ac8410e4afeb40b6d44ed78c145 |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-09T17:15:56Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-18644ac8410e4afeb40b6d44ed78c1452023-11-24T13:36:52ZengMDPI AGBiosensors2079-63742022-12-011212111710.3390/bios12121117Role of Estradiol Hormone in Human Life and Electrochemical Aptasensing of 17β-Estradiol: A ReviewP. P. Waifalkar0Daegwon Noh1Poorva Derashri2Sagar Barage3Eunsoon Oh4Department of Physics, Chungnam National University, Daejeon 34134, Republic of KoreaDepartment of Physics, Chungnam National University, Daejeon 34134, Republic of KoreaAmity Institute of Biotechnology, Amity University, Mumbai-Pune Expressway, Panvel 410206, Maharashtra, IndiaAmity Institute of Biotechnology, Amity University, Mumbai-Pune Expressway, Panvel 410206, Maharashtra, IndiaDepartment of Physics, Chungnam National University, Daejeon 34134, Republic of KoreaEstradiol is known as one of the most potent estrogenic endocrine-disrupting chemicals (EDCs) that may cause various health implications on human growth, metabolism regulation, the reproduction system, and possibly cancers. The detection of these EDCs in our surroundings, such as in foods and beverages, is important to prevent such harmful effects on humans. Aptamers are a promising class of bio-receptors for estradiol detection due to their chemical stability and high affinity. With the development of aptamer technology, electrochemical aptasensing became an important tool for estradiol detection. This review provides detailed information on various technological interventions in electrochemical estradiol detection in solutions and categorized the aptasensing mechanisms, aptamer immobilization strategies, and electrode materials. Moreover, we also discussed the role of estradiol in human physiology and signaling mechanisms. The level of estradiol in circulation is associated with normal and diseased conditions. The aptamer-based electrochemical sensing techniques are powerful and sensitive for estradiol detection.https://www.mdpi.com/2079-6374/12/12/111717β-estradiolelectrochemical aptasensornanomaterialsaptamer immobilizationblocking layer |
| spellingShingle | P. P. Waifalkar Daegwon Noh Poorva Derashri Sagar Barage Eunsoon Oh Role of Estradiol Hormone in Human Life and Electrochemical Aptasensing of 17β-Estradiol: A Review Biosensors 17β-estradiol electrochemical aptasensor nanomaterials aptamer immobilization blocking layer |
| title | Role of Estradiol Hormone in Human Life and Electrochemical Aptasensing of 17β-Estradiol: A Review |
| title_full | Role of Estradiol Hormone in Human Life and Electrochemical Aptasensing of 17β-Estradiol: A Review |
| title_fullStr | Role of Estradiol Hormone in Human Life and Electrochemical Aptasensing of 17β-Estradiol: A Review |
| title_full_unstemmed | Role of Estradiol Hormone in Human Life and Electrochemical Aptasensing of 17β-Estradiol: A Review |
| title_short | Role of Estradiol Hormone in Human Life and Electrochemical Aptasensing of 17β-Estradiol: A Review |
| title_sort | role of estradiol hormone in human life and electrochemical aptasensing of 17β estradiol a review |
| topic | 17β-estradiol electrochemical aptasensor nanomaterials aptamer immobilization blocking layer |
| url | https://www.mdpi.com/2079-6374/12/12/1117 |
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