Selective Syntheses of Coumarin and Benzofuran Derivatives Using Phenols and α-Methoxy-β-ketoesters
Selective syntheses of coumarin and benzofuran derivatives were achieved via HClO4-mediated intermolecular annulation using phenols and α-methoxy-β-ketoesters. Coumarins are formed under dehydrated conditions, whereas benzofurans are formed in the presence of water. In the synthetic process of benzo...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Georg Thieme Verlag KG
2023-01-01
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| Series: | SynOpen |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1751408 |
| _version_ | 1828053189806522368 |
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| author | Ryo Miyata Takashi Shigeta Shigenori Kumazawa Masahiro Egi |
| author_facet | Ryo Miyata Takashi Shigeta Shigenori Kumazawa Masahiro Egi |
| author_sort | Ryo Miyata |
| collection | DOAJ |
| description | Selective syntheses of coumarin and benzofuran derivatives were achieved via HClO4-mediated intermolecular annulation using phenols and α-methoxy-β-ketoesters. Coumarins are formed under dehydrated conditions, whereas benzofurans are formed in the presence of water. In the synthetic process of benzofurans, α-methoxy-β-ketoesters are converted into α-methoxyacetophenones, and the methoxy group is an important element in the intermolecular annulation. |
| first_indexed | 2024-04-10T20:03:16Z |
| format | Article |
| id | doaj.art-1866b928fd03443ea827ceb3fac0f2b2 |
| institution | Directory Open Access Journal |
| issn | 2509-9396 |
| language | English |
| last_indexed | 2024-04-10T20:03:16Z |
| publishDate | 2023-01-01 |
| publisher | Georg Thieme Verlag KG |
| record_format | Article |
| series | SynOpen |
| spelling | doaj.art-1866b928fd03443ea827ceb3fac0f2b22023-01-26T23:49:12ZengGeorg Thieme Verlag KGSynOpen2509-93962023-01-01070181610.1055/s-0042-1751408Selective Syntheses of Coumarin and Benzofuran Derivatives Using Phenols and α-Methoxy-β-ketoestersRyo MiyataTakashi ShigetaShigenori KumazawaMasahiro EgiSelective syntheses of coumarin and benzofuran derivatives were achieved via HClO4-mediated intermolecular annulation using phenols and α-methoxy-β-ketoesters. Coumarins are formed under dehydrated conditions, whereas benzofurans are formed in the presence of water. In the synthetic process of benzofurans, α-methoxy-β-ketoesters are converted into α-methoxyacetophenones, and the methoxy group is an important element in the intermolecular annulation.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1751408coumarinbenzofuranselective synthesesphenolα-methoxy-β-ketoesterα-methoxyacetophenone |
| spellingShingle | Ryo Miyata Takashi Shigeta Shigenori Kumazawa Masahiro Egi Selective Syntheses of Coumarin and Benzofuran Derivatives Using Phenols and α-Methoxy-β-ketoesters SynOpen coumarin benzofuran selective syntheses phenol α-methoxy-β-ketoester α-methoxyacetophenone |
| title | Selective Syntheses of Coumarin and Benzofuran Derivatives Using Phenols and α-Methoxy-β-ketoesters |
| title_full | Selective Syntheses of Coumarin and Benzofuran Derivatives Using Phenols and α-Methoxy-β-ketoesters |
| title_fullStr | Selective Syntheses of Coumarin and Benzofuran Derivatives Using Phenols and α-Methoxy-β-ketoesters |
| title_full_unstemmed | Selective Syntheses of Coumarin and Benzofuran Derivatives Using Phenols and α-Methoxy-β-ketoesters |
| title_short | Selective Syntheses of Coumarin and Benzofuran Derivatives Using Phenols and α-Methoxy-β-ketoesters |
| title_sort | selective syntheses of coumarin and benzofuran derivatives using phenols and α methoxy β ketoesters |
| topic | coumarin benzofuran selective syntheses phenol α-methoxy-β-ketoester α-methoxyacetophenone |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1751408 |
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