DNA methylation as a potential mediator of the association between prenatal tobacco and alcohol exposure and child neurodevelopment in a South African birth cohort

DNA methylation as a potential mediator of the association between prenatal tobacco and alcohol exposure and child neurodevelopment in a South African birth cohort

Abstract Prenatal tobacco exposure (PTE) and prenatal alcohol exposure (PAE) have been associated with an increased risk of delayed neurodevelopment in children as well as differential newborn DNA methylation (DNAm). However, the biological mechanisms connecting PTE and PAE, DNAm, and neurodevelopme...

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Bibliographic Details
Main Authors: Sarina Abrishamcar, Junyu Chen, Dakotah Feil, Anna Kilanowski, Nastassja Koen, Aneesa Vanker, Catherine J. Wedderburn, Kirsten A. Donald, Heather J. Zar, Dan J. Stein, Anke Hüls
Format: Article
Language:English
Published: Nature Publishing Group 2022-09-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-02195-3

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