Comparison of agents and sensitivity profile in urinary tract infection in diabetic and non-diabetic patients
Objective: To study diabetic and non diabetic patients in UTI, regardingthe prevalence of broad spectrum beta-lactamase producing pathogensand quinolone resistance. Methods: Inclusion criteria for this studywas the presence of positive urine culture and fasting glucose equal toor above 126 mg/dl and...
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| Format: | Article |
| Language: | English |
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Instituto Israelita de Ensino e Pesquisa Albert Einstein
2007-12-01
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| Series: | Einstein (São Paulo) |
| Subjects: | |
| Online Access: | http://www.einstein.br/revista/arquivos/PDF/623-Einstein_P1_Vol5N4_Miolo_Pag.363%20a%20367.pdf |
| _version_ | 1811327660085739520 |
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| author | Debora da Silva Krenke Simão Augusto Lottenberg Marines Dalla Valle Martino Jacyr Pasternak |
| author_facet | Debora da Silva Krenke Simão Augusto Lottenberg Marines Dalla Valle Martino Jacyr Pasternak |
| author_sort | Debora da Silva Krenke |
| collection | DOAJ |
| description | Objective: To study diabetic and non diabetic patients in UTI, regardingthe prevalence of broad spectrum beta-lactamase producing pathogensand quinolone resistance. Methods: Inclusion criteria for this studywas the presence of positive urine culture and fasting glucose equal toor above 126 mg/dl and below 100 mg/dl. We managed to include 494patients, 210 diabetics and 284 non-diabetics. Results: Escherichiacoli was the most frequently found pathogen in both diabetic andnon-diabetic groups, and significantly more frequent in non diabeticpatients (p = 0.0001) – 60% to 31% when compared to their diabeticcounterparts. Candida albicans infecting the urinary tract was foundin 30% of diabetics and in 16% of non-diabetics (p = 0.003). Broadspectrum beta-lactamase production was more frequently present inKlebsiella pneumoniae, however without significant difference betweenthe groups. Broad spectrum beta-lactamase production was morefrequent in diabetic patients (12%) than in non-diabetics (4%) (p =0.03). Quinolones resistance was more common in diabetics (40%)when compared to non-diabetics (14%) (p = 0.0001). Escherichiacoli is one of the pathogens more frequently found in patients withUTI. Conclusion: Diabetics have a greater likelihood of developingfungal urinary tract infection by Candida albicans, have more broadspectrum beta-lactamase producing Escherichia coli and more quinolone-resistant pathogens. |
| first_indexed | 2024-04-13T15:11:55Z |
| format | Article |
| id | doaj.art-1869c67a90144455aaf40654e54abb21 |
| institution | Directory Open Access Journal |
| issn | 1679-4508 |
| language | English |
| last_indexed | 2024-04-13T15:11:55Z |
| publishDate | 2007-12-01 |
| publisher | Instituto Israelita de Ensino e Pesquisa Albert Einstein |
| record_format | Article |
| series | Einstein (São Paulo) |
| spelling | doaj.art-1869c67a90144455aaf40654e54abb212022-12-22T02:41:59ZengInstituto Israelita de Ensino e Pesquisa Albert EinsteinEinstein (São Paulo)1679-45082007-12-0154363367Comparison of agents and sensitivity profile in urinary tract infection in diabetic and non-diabetic patientsDebora da Silva KrenkeSimão Augusto LottenbergMarines Dalla Valle MartinoJacyr PasternakObjective: To study diabetic and non diabetic patients in UTI, regardingthe prevalence of broad spectrum beta-lactamase producing pathogensand quinolone resistance. Methods: Inclusion criteria for this studywas the presence of positive urine culture and fasting glucose equal toor above 126 mg/dl and below 100 mg/dl. We managed to include 494patients, 210 diabetics and 284 non-diabetics. Results: Escherichiacoli was the most frequently found pathogen in both diabetic andnon-diabetic groups, and significantly more frequent in non diabeticpatients (p = 0.0001) – 60% to 31% when compared to their diabeticcounterparts. Candida albicans infecting the urinary tract was foundin 30% of diabetics and in 16% of non-diabetics (p = 0.003). Broadspectrum beta-lactamase production was more frequently present inKlebsiella pneumoniae, however without significant difference betweenthe groups. Broad spectrum beta-lactamase production was morefrequent in diabetic patients (12%) than in non-diabetics (4%) (p =0.03). Quinolones resistance was more common in diabetics (40%)when compared to non-diabetics (14%) (p = 0.0001). Escherichiacoli is one of the pathogens more frequently found in patients withUTI. Conclusion: Diabetics have a greater likelihood of developingfungal urinary tract infection by Candida albicans, have more broadspectrum beta-lactamase producing Escherichia coli and more quinolone-resistant pathogens.http://www.einstein.br/revista/arquivos/PDF/623-Einstein_P1_Vol5N4_Miolo_Pag.363%20a%20367.pdfDiabetes mellitusUrinary tractUrinary tract infectionsDrug resistancebacterial |
| spellingShingle | Debora da Silva Krenke Simão Augusto Lottenberg Marines Dalla Valle Martino Jacyr Pasternak Comparison of agents and sensitivity profile in urinary tract infection in diabetic and non-diabetic patients Einstein (São Paulo) Diabetes mellitus Urinary tract Urinary tract infections Drug resistance bacterial |
| title | Comparison of agents and sensitivity profile in urinary tract infection in diabetic and non-diabetic patients |
| title_full | Comparison of agents and sensitivity profile in urinary tract infection in diabetic and non-diabetic patients |
| title_fullStr | Comparison of agents and sensitivity profile in urinary tract infection in diabetic and non-diabetic patients |
| title_full_unstemmed | Comparison of agents and sensitivity profile in urinary tract infection in diabetic and non-diabetic patients |
| title_short | Comparison of agents and sensitivity profile in urinary tract infection in diabetic and non-diabetic patients |
| title_sort | comparison of agents and sensitivity profile in urinary tract infection in diabetic and non diabetic patients |
| topic | Diabetes mellitus Urinary tract Urinary tract infections Drug resistance bacterial |
| url | http://www.einstein.br/revista/arquivos/PDF/623-Einstein_P1_Vol5N4_Miolo_Pag.363%20a%20367.pdf |
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