The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer
Despite some well-characterized functions in cancer, the impact of most long non-coding RNAs remains unknown. Here, the authors discover the lncRNA lincNMR which is upregulated in cancer and drives cell proliferation by interacting with YBX1 and controlling nucleotide metabolism.
Bibliographic Details
| Main Authors: |
Minakshi Gandhi,
Matthias Groß,
Jessica M. Holler,
Si’Ana A. Coggins,
Nitin Patil,
Joerg H. Leupold,
Mathias Munschauer,
Monica Schenone,
Christina R. Hartigan,
Heike Allgayer,
Baek Kim,
Sven Diederichs |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2020-06-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-17007-9
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