Cohort study of osteoporosis and fracture risk in Wales: does secondary prevention achieve any benefit?
Background Osteoporosis is a global disease with a 30-40% lifetime fracture risk according to the World Health Organisation. Incidence is rising with aging populations; however, medical secondary prevention treatment may reduce fracture risk. Objectives The primary aim was to investigate if secon...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Swansea University
2018-06-01
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| Series: | International Journal of Population Data Science |
| Online Access: | https://ijpds.org/article/view/510 |
| _version_ | 1797422345379381248 |
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| author | Laura North Llion Davies Damon Berridge Angharad Walters Ashley Akbari Ronan Lyons |
| author_facet | Laura North Llion Davies Damon Berridge Angharad Walters Ashley Akbari Ronan Lyons |
| author_sort | Laura North |
| collection | DOAJ |
| description | Background
Osteoporosis is a global disease with a 30-40% lifetime fracture risk according to the World Health Organisation. Incidence is rising with aging populations; however, medical secondary prevention treatment may reduce fracture risk.
Objectives
The primary aim was to investigate if secondary medical prevention treatment following an index fracture was associated with survival and subsequent fracture risk.
Methods
Patients aged ≥60 years with an index fragility fracture at any anatomical location were identified from the Secure Anonymised Information Linkage (SAIL) databank. A population based e-cohort was created by linking fracture data identified from secondary care datasets and the National Hip Fracture Register data, with linkages to primary care datasets for medical prescription and Office for National Statistics records for mortality.
Findings
The cohort comprised 81,252 cases between April 2009 and December 2016 of median age 78 years and 22,896 (28%) males. Medical secondary prevention treatment was received by 29,393 cases (36%). Subsequent fractures were reported for 10,907 cases (13%) and 29,026 cases (36%) died during the study period.
Conclusions
Preliminary findings identified that <50% of eligible patients receive secondary medical prevention treatment after an index fragility fracture. These findings may help inform and unify treatment pathways for those at risk of fragility fractures. |
| first_indexed | 2024-03-09T07:31:56Z |
| format | Article |
| id | doaj.art-186cf06ade0943cdb926bbda42406972 |
| institution | Directory Open Access Journal |
| issn | 2399-4908 |
| language | English |
| last_indexed | 2024-03-09T07:31:56Z |
| publishDate | 2018-06-01 |
| publisher | Swansea University |
| record_format | Article |
| series | International Journal of Population Data Science |
| spelling | doaj.art-186cf06ade0943cdb926bbda424069722023-12-03T06:08:04ZengSwansea UniversityInternational Journal of Population Data Science2399-49082018-06-013210.23889/ijpds.v3i2.510510Cohort study of osteoporosis and fracture risk in Wales: does secondary prevention achieve any benefit?Laura North0Llion Davies1Damon Berridge2Angharad Walters3Ashley Akbari4Ronan Lyons5Farr Institute, Swansea University Medical SchoolPublic Health WalesFarr Institute, Swansea University Medical SchoolFarr Institute, Swansea University Medical SchoolFarr Institute, Swansea University Medical SchoolFarr Institute, Swansea University Medical SchoolBackground Osteoporosis is a global disease with a 30-40% lifetime fracture risk according to the World Health Organisation. Incidence is rising with aging populations; however, medical secondary prevention treatment may reduce fracture risk. Objectives The primary aim was to investigate if secondary medical prevention treatment following an index fracture was associated with survival and subsequent fracture risk. Methods Patients aged ≥60 years with an index fragility fracture at any anatomical location were identified from the Secure Anonymised Information Linkage (SAIL) databank. A population based e-cohort was created by linking fracture data identified from secondary care datasets and the National Hip Fracture Register data, with linkages to primary care datasets for medical prescription and Office for National Statistics records for mortality. Findings The cohort comprised 81,252 cases between April 2009 and December 2016 of median age 78 years and 22,896 (28%) males. Medical secondary prevention treatment was received by 29,393 cases (36%). Subsequent fractures were reported for 10,907 cases (13%) and 29,026 cases (36%) died during the study period. Conclusions Preliminary findings identified that <50% of eligible patients receive secondary medical prevention treatment after an index fragility fracture. These findings may help inform and unify treatment pathways for those at risk of fragility fractures.https://ijpds.org/article/view/510 |
| spellingShingle | Laura North Llion Davies Damon Berridge Angharad Walters Ashley Akbari Ronan Lyons Cohort study of osteoporosis and fracture risk in Wales: does secondary prevention achieve any benefit? International Journal of Population Data Science |
| title | Cohort study of osteoporosis and fracture risk in Wales: does secondary prevention achieve any benefit? |
| title_full | Cohort study of osteoporosis and fracture risk in Wales: does secondary prevention achieve any benefit? |
| title_fullStr | Cohort study of osteoporosis and fracture risk in Wales: does secondary prevention achieve any benefit? |
| title_full_unstemmed | Cohort study of osteoporosis and fracture risk in Wales: does secondary prevention achieve any benefit? |
| title_short | Cohort study of osteoporosis and fracture risk in Wales: does secondary prevention achieve any benefit? |
| title_sort | cohort study of osteoporosis and fracture risk in wales does secondary prevention achieve any benefit |
| url | https://ijpds.org/article/view/510 |
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