Applicability of major histocompatibility complex DRB1 alleles as markers to detect vertebrate hybridization: a case study from Iberian ibex × domestic goat in southern Spain
<p>Abstract</p> <p>Background</p> <p>Hybridization between closely related wild and domestic species is of great concern because it can alter the evolutionary integrity of the affected populations. The high allelic variability of Major Histocompatibility Complex (MHC) l...
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| Format: | Article |
| Language: | English |
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BMC
2012-09-01
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| Series: | Acta Veterinaria Scandinavica |
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| Online Access: | http://www.actavetscand.com/content/54/1/56 |
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| author | Alasaad Samer Fickel Joerns Rossi Luca Sarasa Mathieu BenÃ-tez-Camacho Buenaventura Granados José E Soriguer Ramón C |
| author_facet | Alasaad Samer Fickel Joerns Rossi Luca Sarasa Mathieu BenÃ-tez-Camacho Buenaventura Granados José E Soriguer Ramón C |
| author_sort | Alasaad Samer |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Hybridization between closely related wild and domestic species is of great concern because it can alter the evolutionary integrity of the affected populations. The high allelic variability of Major Histocompatibility Complex (MHC) loci usually excludes them from being used in studies to detect hybridization events. However, if a) the parental species don’t share alleles, and b) one of the parental species possesses an exceptionally low number of alleles (to facilitate analysis), then even MHC loci have the potential to detect hybrids.</p> <p>Results</p> <p>By genotyping the exon2 of the MHC class II DRB1 locus, we were able to detect hybridization between domestic goats (<it>Capra hircus</it>) and free-ranging Iberian ibex (<it>Capra pyrenaica hispanica</it>) by molecular means.</p> <p>Conclusions</p> <p>This is the first documentation of a <it>Capra pyrenaica</it> × <it>Capra hircus</it> hybridization, which presented us the opportunity to test the applicability of MHC loci as new, simple, cost-effective, and time-saving approach to detect hybridization between wild species and their domesticated relatives, thus adding value to MHC genes role in animal conservation and management.</p> |
| first_indexed | 2024-12-11T13:13:44Z |
| format | Article |
| id | doaj.art-186d7e5a2f0042978811d1dde79b924a |
| institution | Directory Open Access Journal |
| issn | 1751-0147 |
| language | English |
| last_indexed | 2024-12-11T13:13:44Z |
| publishDate | 2012-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Acta Veterinaria Scandinavica |
| spelling | doaj.art-186d7e5a2f0042978811d1dde79b924a2022-12-22T01:06:06ZengBMCActa Veterinaria Scandinavica1751-01472012-09-015415610.1186/1751-0147-54-56Applicability of major histocompatibility complex DRB1 alleles as markers to detect vertebrate hybridization: a case study from Iberian ibex × domestic goat in southern SpainAlasaad SamerFickel JoernsRossi LucaSarasa MathieuBenÃ-tez-Camacho BuenaventuraGranados José ESoriguer Ramón C<p>Abstract</p> <p>Background</p> <p>Hybridization between closely related wild and domestic species is of great concern because it can alter the evolutionary integrity of the affected populations. The high allelic variability of Major Histocompatibility Complex (MHC) loci usually excludes them from being used in studies to detect hybridization events. However, if a) the parental species don’t share alleles, and b) one of the parental species possesses an exceptionally low number of alleles (to facilitate analysis), then even MHC loci have the potential to detect hybrids.</p> <p>Results</p> <p>By genotyping the exon2 of the MHC class II DRB1 locus, we were able to detect hybridization between domestic goats (<it>Capra hircus</it>) and free-ranging Iberian ibex (<it>Capra pyrenaica hispanica</it>) by molecular means.</p> <p>Conclusions</p> <p>This is the first documentation of a <it>Capra pyrenaica</it> × <it>Capra hircus</it> hybridization, which presented us the opportunity to test the applicability of MHC loci as new, simple, cost-effective, and time-saving approach to detect hybridization between wild species and their domesticated relatives, thus adding value to MHC genes role in animal conservation and management.</p>http://www.actavetscand.com/content/54/1/56HybridizationMHC allelesCapra pyrenaicaCapra hircusWildlife conservation |
| spellingShingle | Alasaad Samer Fickel Joerns Rossi Luca Sarasa Mathieu BenÃ-tez-Camacho Buenaventura Granados José E Soriguer Ramón C Applicability of major histocompatibility complex DRB1 alleles as markers to detect vertebrate hybridization: a case study from Iberian ibex × domestic goat in southern Spain Acta Veterinaria Scandinavica Hybridization MHC alleles Capra pyrenaica Capra hircus Wildlife conservation |
| title | Applicability of major histocompatibility complex DRB1 alleles as markers to detect vertebrate hybridization: a case study from Iberian ibex × domestic goat in southern Spain |
| title_full | Applicability of major histocompatibility complex DRB1 alleles as markers to detect vertebrate hybridization: a case study from Iberian ibex × domestic goat in southern Spain |
| title_fullStr | Applicability of major histocompatibility complex DRB1 alleles as markers to detect vertebrate hybridization: a case study from Iberian ibex × domestic goat in southern Spain |
| title_full_unstemmed | Applicability of major histocompatibility complex DRB1 alleles as markers to detect vertebrate hybridization: a case study from Iberian ibex × domestic goat in southern Spain |
| title_short | Applicability of major histocompatibility complex DRB1 alleles as markers to detect vertebrate hybridization: a case study from Iberian ibex × domestic goat in southern Spain |
| title_sort | applicability of major histocompatibility complex drb1 alleles as markers to detect vertebrate hybridization a case study from iberian ibex domestic goat in southern spain |
| topic | Hybridization MHC alleles Capra pyrenaica Capra hircus Wildlife conservation |
| url | http://www.actavetscand.com/content/54/1/56 |
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