Bridging Radiotherapy to Immunotherapy: The IFN–JAK–STAT Axis

Bridging Radiotherapy to Immunotherapy: The IFN–JAK–STAT Axis

The unprecedented successes of immunotherapies (IOs) including immune checkpoint blockers (ICBs) and adoptive T-cell therapy (ACT) in patients with late-stage cancer provide proof-of-principle evidence that harnessing the immune system, in particular T cells, can be an effective approach to eradicat...

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Bibliographic Details
Main Authors: Lewis Zhichang Shi, James A. Bonner
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
radiotherapy
immunotherapy
interferon
IFN-γ
JAK
STAT
Online Access:https://www.mdpi.com/1422-0067/22/22/12295

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