Mechanochemical Synthesis of the Catechol-Theophylline Cocrystal: Spectroscopic Characterization and Molecular Structure

Mechanochemical Synthesis of the Catechol-Theophylline Cocrystal: Spectroscopic Characterization and Molecular Structure

Pharmaceutical cocrystallization offers the possibility to modify the physicochemical and biopharmaceutical properties of active pharmaceutical ingredients. The mechanochemical synthesis and spectroscopic characterization of the catechol-theophylline (CAT-TEO) cocrystal is reported. The cocrystal wa...

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Bibliographic Details
Main Authors: Juan Saulo González-González, Raquel Jiménez-López, David Ortegón-Reyna, Gabino Gonzalez-Carrillo, Francisco Javier Martínez-Martínez
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Applied Sciences
Subjects:
cocrystal
theophylline
catechol
IR spectroscopy
theoretical calculations
Online Access:https://www.mdpi.com/2076-3417/11/9/3810

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