Induced sputum MMP-1, -3 & -8 concentrations during treatment of tuberculosis.
Tuberculosis (TB) destroys lung tissues and this immunopathology is mediated in part by Matrix Metalloproteinases (MMPs). There are no data on the relationship between local tissue MMPs concentrations, anti-tuberculosis therapy and sputum conversion.Induced sputum was collected from 68 TB patients a...
Main Authors: | Cesar A Ugarte-Gil, Paul Elkington, Robert H Gilman, Jorge Coronel, Liku B Tezera, Antonio Bernabe-Ortiz, Eduardo Gotuzzo, Jon S Friedland, David A J Moore |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3632571?pdf=render |
Similar Items
-
Anti-Tuberculosis Activity of Three Carbapenems, Clofazimine and Nitazoxanide Using a Novel Ex Vivo Phenotypic Drug Susceptibility Model of Human Tuberculosis
by: Ximena Gonzalo, et al.
Published: (2022-09-01) -
<it>Evaluation of bleach-sedimentation for sterilising and concentrating </it>Mycobacterium tuberculosis <it>in sputum specimens</it>
by: Valencia Teresa, et al.
Published: (2011-10-01) -
<it>Mycobacterium tuberculosis</it>-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNFα, NFκB, p38 and caspase 8 dependent pathways
by: Elkington Paul T, et al.
Published: (2011-05-01) -
Mycobacterium tuberculosis senses host Interferon-γ via the membrane protein MmpL10
by: Mohamed Ahmed, et al.
Published: (2022-12-01) -
A Bioengineered Three-Dimensional Cell Culture Platform Integrated with Microfluidics To Address Antimicrobial Resistance in Tuberculosis
by: Magdalena K. Bielecka, et al.
Published: (2017-03-01)