A Rare Presentation of Lupus Nephritis Flare up with Posterior Reversible Leucoencephalopathy

Systemic lupus erythematosus (SLE) is associated with various neurologic or psychiatric abnormalities and Posterior Reversible Leuco Encephalopathy Syndrome (PRES) is very rare neurological manifestation in SLE. PRES is associated with various clinical manifestations, like, seizures, visual loss,...

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Main Authors: S. Hima Mani, S. M. Shivaprasad, L. Umesh
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2016-01-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/7038/14770_CE[Ra]_F(Sh)_PF1(VIAK)_PFA(NC_AK)_PF2(PAG).pdf
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author S. Hima Mani
S. M. Shivaprasad
L. Umesh
author_facet S. Hima Mani
S. M. Shivaprasad
L. Umesh
author_sort S. Hima Mani
collection DOAJ
description Systemic lupus erythematosus (SLE) is associated with various neurologic or psychiatric abnormalities and Posterior Reversible Leuco Encephalopathy Syndrome (PRES) is very rare neurological manifestation in SLE. PRES is associated with various clinical manifestations, like, seizures, visual loss, headaches, vomiting altered mental status and rarely focal neurological deficits. Other predisposing condition associated with PRES is eclampsia, accelerated hypertension, uraemia, transplantation, autoimmune diseases and/or use of immunosuppressive drugs. It is important to recognise PRES since it is a potentially reversible. We describe an unusual case of PRES caused by uraemia during lupus flare up in a patient with biopsy proven class IV lupus nephritis who presented with features of asymmetrical quadriparesis which completely reversed after haemodialysis sessions and treating lupus flare up. In our case she presented with quadriparesis which is a rare presentation and hypertensive encephalopathy was not present.
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spelling doaj.art-1876780cda66455ea75a93c5f51579482022-12-21T19:27:59ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-01-01101OD03OD0410.7860/JCDR/2016/14770.7038A Rare Presentation of Lupus Nephritis Flare up with Posterior Reversible LeucoencephalopathyS. Hima Mani0S. M. Shivaprasad1L. Umesh2Post Graduate Student, Department of Nephrology, Institute of Nephrourology, Bangalore, India.Associate Professor, Department of Nephrology, Institute of Nephrourology, Bangalore, India.Professor and Head, Department of Nephrology, Institute of Nephrourology, Bangalore, India.Systemic lupus erythematosus (SLE) is associated with various neurologic or psychiatric abnormalities and Posterior Reversible Leuco Encephalopathy Syndrome (PRES) is very rare neurological manifestation in SLE. PRES is associated with various clinical manifestations, like, seizures, visual loss, headaches, vomiting altered mental status and rarely focal neurological deficits. Other predisposing condition associated with PRES is eclampsia, accelerated hypertension, uraemia, transplantation, autoimmune diseases and/or use of immunosuppressive drugs. It is important to recognise PRES since it is a potentially reversible. We describe an unusual case of PRES caused by uraemia during lupus flare up in a patient with biopsy proven class IV lupus nephritis who presented with features of asymmetrical quadriparesis which completely reversed after haemodialysis sessions and treating lupus flare up. In our case she presented with quadriparesis which is a rare presentation and hypertensive encephalopathy was not present.https://jcdr.net/articles/PDF/7038/14770_CE[Ra]_F(Sh)_PF1(VIAK)_PFA(NC_AK)_PF2(PAG).pdf(hbp) high blood pressurenih (national institute of health)sle- systemic lupus nephritis
spellingShingle S. Hima Mani
S. M. Shivaprasad
L. Umesh
A Rare Presentation of Lupus Nephritis Flare up with Posterior Reversible Leucoencephalopathy
Journal of Clinical and Diagnostic Research
(hbp) high blood pressure
nih (national institute of health)
sle- systemic lupus nephritis
title A Rare Presentation of Lupus Nephritis Flare up with Posterior Reversible Leucoencephalopathy
title_full A Rare Presentation of Lupus Nephritis Flare up with Posterior Reversible Leucoencephalopathy
title_fullStr A Rare Presentation of Lupus Nephritis Flare up with Posterior Reversible Leucoencephalopathy
title_full_unstemmed A Rare Presentation of Lupus Nephritis Flare up with Posterior Reversible Leucoencephalopathy
title_short A Rare Presentation of Lupus Nephritis Flare up with Posterior Reversible Leucoencephalopathy
title_sort rare presentation of lupus nephritis flare up with posterior reversible leucoencephalopathy
topic (hbp) high blood pressure
nih (national institute of health)
sle- systemic lupus nephritis
url https://jcdr.net/articles/PDF/7038/14770_CE[Ra]_F(Sh)_PF1(VIAK)_PFA(NC_AK)_PF2(PAG).pdf
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