FEVER AS INDICATOR TO SECONDARY INFECTION IN DENGUE VIRAL INFECTION

Dengue Virus Infections are distributed in tropical and sub-tropical regions and transmitted by the mosquitoes such as Aedes aegypti and Aedes albopictus. Dengue virus can cause dengue fever, dengue hemorrhagic fever and dengue shock syndrome or dengue and severe dengue classified by World Health Or...

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Main Authors: Soegeng Soegijanto, Sufiandika Nuryandari, Siti Churrotin, Teguh Hari Sucipto
Format: Article
Language:English
Published: Universitas Airlangga 2018-03-01
Series:Indonesian Journal of Tropical and Infectious Disease
Subjects:
Online Access:https://e-journal.unair.ac.id/IJTID/article/view/5640
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author Soegeng Soegijanto
Sufiandika Nuryandari
Siti Churrotin
Teguh Hari Sucipto
author_facet Soegeng Soegijanto
Sufiandika Nuryandari
Siti Churrotin
Teguh Hari Sucipto
author_sort Soegeng Soegijanto
collection DOAJ
description Dengue Virus Infections are distributed in tropical and sub-tropical regions and transmitted by the mosquitoes such as Aedes aegypti and Aedes albopictus. Dengue virus can cause dengue fever, dengue hemorrhagic fever and dengue shock syndrome or dengue and severe dengue classified by World Health Organization. Beside it concurrent infection virus salmonella had been found some cases who showed fever more than 7 days. Concurrent infection with two agents can result in an illness having overlapping symptoms creating a diagnostic dilemma for treating physician, such as dengue fever with typhoid fever. The aim of this research is detection of dengue virus and secondary infection with Salmonella typhi in patients suspected dengue virus infection. Detection of dengue virus and Salmonella typhi using immunochromatography test such as NS1, IgG/IgM for dengue virus infection, and IgM/IgG Salmonella and blood culture. The fifty children with dengue virus infection came to Soerya hospital and 17 cases suspected dengue virus infection, five cases showed a positive NS1 on the second day of fever and one case concurrent with clinical manifestation of convulsi on the third days of fever there were five cases only showed positive. It was showed in this study that on the fourth to six day of fever in dengue virus infection accompanied by antibody IgM & IgG dengue. There were 12 cases showed the clinical manifestation of concurrent dengue viral infection and Salmonella, all of them showed a mild clinical manifestation and did not show plasma leakage and shock. In this study we found the length of stay of concurrent Dengue Virus Infection and Salmonella infection is more than 10 days. These patients were also more likely to have co-existing haemodynamic disturbances and bacterial septicaemia which would have required treatment with inotropes and antibiotics. This idea is very important to make update dengue viral management to decrease mortality in outbreak try to gain new prevention method before the occurrence of outbreak.
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spelling doaj.art-1876a0f9cf0645fab4baeb6f12df8b372022-12-21T20:12:20ZengUniversitas AirlanggaIndonesian Journal of Tropical and Infectious Disease2085-11032356-09912018-03-0171212510.20473/ijtid.v7i1.56404189FEVER AS INDICATOR TO SECONDARY INFECTION IN DENGUE VIRAL INFECTIONSoegeng Soegijanto0Sufiandika Nuryandari1Siti Churrotin2Teguh Hari Sucipto31. Faculty of Medicine, Universitas Airlangga, Indonesia 2. Dengue Study Group, Institute of Tropical Disease, Universitas Airlangga, IndonesiaMother and child Hospital of Soerya, IndonesiaDengue Study Group, Institute of Tropical Disease, Universitas Airlangga, IndonesiaDengue Study Group, Institute of Tropical Disease, Universitas Airlangga, IndonesiaDengue Virus Infections are distributed in tropical and sub-tropical regions and transmitted by the mosquitoes such as Aedes aegypti and Aedes albopictus. Dengue virus can cause dengue fever, dengue hemorrhagic fever and dengue shock syndrome or dengue and severe dengue classified by World Health Organization. Beside it concurrent infection virus salmonella had been found some cases who showed fever more than 7 days. Concurrent infection with two agents can result in an illness having overlapping symptoms creating a diagnostic dilemma for treating physician, such as dengue fever with typhoid fever. The aim of this research is detection of dengue virus and secondary infection with Salmonella typhi in patients suspected dengue virus infection. Detection of dengue virus and Salmonella typhi using immunochromatography test such as NS1, IgG/IgM for dengue virus infection, and IgM/IgG Salmonella and blood culture. The fifty children with dengue virus infection came to Soerya hospital and 17 cases suspected dengue virus infection, five cases showed a positive NS1 on the second day of fever and one case concurrent with clinical manifestation of convulsi on the third days of fever there were five cases only showed positive. It was showed in this study that on the fourth to six day of fever in dengue virus infection accompanied by antibody IgM & IgG dengue. There were 12 cases showed the clinical manifestation of concurrent dengue viral infection and Salmonella, all of them showed a mild clinical manifestation and did not show plasma leakage and shock. In this study we found the length of stay of concurrent Dengue Virus Infection and Salmonella infection is more than 10 days. These patients were also more likely to have co-existing haemodynamic disturbances and bacterial septicaemia which would have required treatment with inotropes and antibiotics. This idea is very important to make update dengue viral management to decrease mortality in outbreak try to gain new prevention method before the occurrence of outbreak.https://e-journal.unair.ac.id/IJTID/article/view/5640dengue viralsalmonella typhico-infectionsecondary infectionlaboratory test
spellingShingle Soegeng Soegijanto
Sufiandika Nuryandari
Siti Churrotin
Teguh Hari Sucipto
FEVER AS INDICATOR TO SECONDARY INFECTION IN DENGUE VIRAL INFECTION
Indonesian Journal of Tropical and Infectious Disease
dengue viral
salmonella typhi
co-infection
secondary infection
laboratory test
title FEVER AS INDICATOR TO SECONDARY INFECTION IN DENGUE VIRAL INFECTION
title_full FEVER AS INDICATOR TO SECONDARY INFECTION IN DENGUE VIRAL INFECTION
title_fullStr FEVER AS INDICATOR TO SECONDARY INFECTION IN DENGUE VIRAL INFECTION
title_full_unstemmed FEVER AS INDICATOR TO SECONDARY INFECTION IN DENGUE VIRAL INFECTION
title_short FEVER AS INDICATOR TO SECONDARY INFECTION IN DENGUE VIRAL INFECTION
title_sort fever as indicator to secondary infection in dengue viral infection
topic dengue viral
salmonella typhi
co-infection
secondary infection
laboratory test
url https://e-journal.unair.ac.id/IJTID/article/view/5640
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AT sufiandikanuryandari feverasindicatortosecondaryinfectionindengueviralinfection
AT sitichurrotin feverasindicatortosecondaryinfectionindengueviralinfection
AT teguhharisucipto feverasindicatortosecondaryinfectionindengueviralinfection