Comparison of the clinical effects of intermittently scanned and real‐time continuous glucose monitoring in children and adolescents with type 1 diabetes: A retrospective cohort study
ABSTRACT Aims/Introduction The aim of the study was to compare two continuous glucose monitoring (CGM) systems, intermittently scanned CGM (isCGM) and real‐time CGM (rtCGM), to determine which system achieved better glycemic control in pediatric patients. Materials and Methods We carried out a retro...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-10-01
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| Series: | Journal of Diabetes Investigation |
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| Online Access: | https://doi.org/10.1111/jdi.13830 |
| _version_ | 1817981925667635200 |
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| author | Tatsuhiko Urakami Hiroki Terada Kei Yoshida Remi Kuwabara Yusuke Mine Masako Aoki Yasuko Shoji Junichi Suzuki Ichiro Morioka |
| author_facet | Tatsuhiko Urakami Hiroki Terada Kei Yoshida Remi Kuwabara Yusuke Mine Masako Aoki Yasuko Shoji Junichi Suzuki Ichiro Morioka |
| author_sort | Tatsuhiko Urakami |
| collection | DOAJ |
| description | ABSTRACT Aims/Introduction The aim of the study was to compare two continuous glucose monitoring (CGM) systems, intermittently scanned CGM (isCGM) and real‐time CGM (rtCGM), to determine which system achieved better glycemic control in pediatric patients. Materials and Methods We carried out a retrospective cohort study of children and adolescents with type 1 diabetes, and compared the time in range (70–180 mg/dL), time below range (<70 mg/dL) and time above range (>180 mg/dL), and estimated glycated hemoglobin levels between patients on isCGM and rtCGM. Results Of the 112 participants, 76 (67.9%) used isCGM and 36 (32.1%) used rtCGM for glycemic management. Patients on rtCGM had significantly greater time in range (57.7 ± 12.3% vs 52.3 ± 12.3%, P = 0.0368), and had significantly lower time below range (4.3 ± 2.7% vs 10.2% ± 5.4%, P < 0.001) than those on isCGM, but there was no significant difference in the time above range (37.4 ± 12.9% vs 38.0% ± 12.5%, P = 0.881) or the glycosylated hemoglobin A1c levels (7.4 ± 0.9% vs 7.5 ± 0.8%, P = 0.734) between the two groups. Conclusions Pediatric patients with type 1 diabetes on rtCGM also showed more beneficial effects for increase of time in range, with a notable reduction of time below range compared with those on isCGM. Real‐time CGM might provide better glycemic control than isCGM in children with type 1 diabetes. |
| first_indexed | 2024-04-13T23:12:36Z |
| format | Article |
| id | doaj.art-187ac2fdc00b4a6593359f79bb50928c |
| institution | Directory Open Access Journal |
| issn | 2040-1116 2040-1124 |
| language | English |
| last_indexed | 2024-04-13T23:12:36Z |
| publishDate | 2022-10-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Investigation |
| spelling | doaj.art-187ac2fdc00b4a6593359f79bb50928c2022-12-22T02:25:30ZengWileyJournal of Diabetes Investigation2040-11162040-11242022-10-0113101745175210.1111/jdi.13830Comparison of the clinical effects of intermittently scanned and real‐time continuous glucose monitoring in children and adolescents with type 1 diabetes: A retrospective cohort studyTatsuhiko Urakami0Hiroki Terada1Kei Yoshida2Remi Kuwabara3Yusuke Mine4Masako Aoki5Yasuko Shoji6Junichi Suzuki7Ichiro Morioka8Department of Pediatrics Nihon University School of Medicine Tokyo JapanDepartment of Pediatrics Nihon University School of Medicine Tokyo JapanDepartment of Pediatrics Nihon University School of Medicine Tokyo JapanDepartment of Pediatrics Nihon University School of Medicine Tokyo JapanDepartment of Pediatrics Nihon University School of Medicine Tokyo JapanDepartment of Pediatrics Nihon University School of Medicine Tokyo JapanDepartment of Pediatrics Nihon University School of Medicine Tokyo JapanDepartment of Pediatrics Nihon University School of Medicine Tokyo JapanDepartment of Pediatrics Nihon University School of Medicine Tokyo JapanABSTRACT Aims/Introduction The aim of the study was to compare two continuous glucose monitoring (CGM) systems, intermittently scanned CGM (isCGM) and real‐time CGM (rtCGM), to determine which system achieved better glycemic control in pediatric patients. Materials and Methods We carried out a retrospective cohort study of children and adolescents with type 1 diabetes, and compared the time in range (70–180 mg/dL), time below range (<70 mg/dL) and time above range (>180 mg/dL), and estimated glycated hemoglobin levels between patients on isCGM and rtCGM. Results Of the 112 participants, 76 (67.9%) used isCGM and 36 (32.1%) used rtCGM for glycemic management. Patients on rtCGM had significantly greater time in range (57.7 ± 12.3% vs 52.3 ± 12.3%, P = 0.0368), and had significantly lower time below range (4.3 ± 2.7% vs 10.2% ± 5.4%, P < 0.001) than those on isCGM, but there was no significant difference in the time above range (37.4 ± 12.9% vs 38.0% ± 12.5%, P = 0.881) or the glycosylated hemoglobin A1c levels (7.4 ± 0.9% vs 7.5 ± 0.8%, P = 0.734) between the two groups. Conclusions Pediatric patients with type 1 diabetes on rtCGM also showed more beneficial effects for increase of time in range, with a notable reduction of time below range compared with those on isCGM. Real‐time CGM might provide better glycemic control than isCGM in children with type 1 diabetes.https://doi.org/10.1111/jdi.13830Continuous glucose monitoringHypoglycemiaType 1 diabetes |
| spellingShingle | Tatsuhiko Urakami Hiroki Terada Kei Yoshida Remi Kuwabara Yusuke Mine Masako Aoki Yasuko Shoji Junichi Suzuki Ichiro Morioka Comparison of the clinical effects of intermittently scanned and real‐time continuous glucose monitoring in children and adolescents with type 1 diabetes: A retrospective cohort study Journal of Diabetes Investigation Continuous glucose monitoring Hypoglycemia Type 1 diabetes |
| title | Comparison of the clinical effects of intermittently scanned and real‐time continuous glucose monitoring in children and adolescents with type 1 diabetes: A retrospective cohort study |
| title_full | Comparison of the clinical effects of intermittently scanned and real‐time continuous glucose monitoring in children and adolescents with type 1 diabetes: A retrospective cohort study |
| title_fullStr | Comparison of the clinical effects of intermittently scanned and real‐time continuous glucose monitoring in children and adolescents with type 1 diabetes: A retrospective cohort study |
| title_full_unstemmed | Comparison of the clinical effects of intermittently scanned and real‐time continuous glucose monitoring in children and adolescents with type 1 diabetes: A retrospective cohort study |
| title_short | Comparison of the clinical effects of intermittently scanned and real‐time continuous glucose monitoring in children and adolescents with type 1 diabetes: A retrospective cohort study |
| title_sort | comparison of the clinical effects of intermittently scanned and real time continuous glucose monitoring in children and adolescents with type 1 diabetes a retrospective cohort study |
| topic | Continuous glucose monitoring Hypoglycemia Type 1 diabetes |
| url | https://doi.org/10.1111/jdi.13830 |
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