Chemical Composition, Antibacterial and Phytotoxic Activities of Peganum harmala Seed Essential Oils from Five Different Localities in Northern Africa
Peganum harmala L., also known as Syrian rue or Pègano, is a herbaceous plant belonging to the Zygohpyllaceae family, and is widely used in traditional medicine. The chemical composition of essential oils of P. harmala seeds from five different regions of Northern Africa (Algeria, Egypt, Libya, Moro...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2016-09-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1420-3049/21/9/1235 |
| _version_ | 1819139658887462912 |
|---|---|
| author | Ida Apostolico Luigi Aliberti Lucia Caputo Vincenzo De Feo Florinda Fratianni Filomena Nazzaro Lucèia Fàtima Souza Maroua Khadhr |
| author_facet | Ida Apostolico Luigi Aliberti Lucia Caputo Vincenzo De Feo Florinda Fratianni Filomena Nazzaro Lucèia Fàtima Souza Maroua Khadhr |
| author_sort | Ida Apostolico |
| collection | DOAJ |
| description | Peganum harmala L., also known as Syrian rue or Pègano, is a herbaceous plant belonging to the Zygohpyllaceae family, and is widely used in traditional medicine. The chemical composition of essential oils of P. harmala seeds from five different regions of Northern Africa (Algeria, Egypt, Libya, Morocco and Tunisia) was studied by GC and GC-MS analyses. A total of 105 compounds were identified, the main components being oxygenated monoterpenes and oxygenated sesquiterpenes. Eugenol is the main component in all oils. The antimicrobial activity of the essential oils was assayed against some bacterial strains: Staphylococcus aureus (DSM 25693), Bacillus cereus (DSM 4313), Bacillus cereus (DSM4384), Escherichia coli (DMS 857) and Pseudomonas aeruginosa (ATCC 50071). All the oils showed different inhibitory activity. In the twentieth century this is an important result; we need possible new botanical drugs because the problem of resistance to antimicrobial drugs has become apparent. Moreover, the essential oils were evaluated for their possible in vitro phytotoxic activity against germination and initial radicle growth of Raphanus sativus L., Lepidium sativum L., and Ruta graveolens L. The results showed that both germination and radical elongation were sensitive to the oils. |
| first_indexed | 2024-12-22T11:26:10Z |
| format | Article |
| id | doaj.art-187bc6f4bcbc4364976b2d53133e9a60 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-22T11:26:10Z |
| publishDate | 2016-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-187bc6f4bcbc4364976b2d53133e9a602022-12-21T18:27:44ZengMDPI AGMolecules1420-30492016-09-01219123510.3390/molecules21091235molecules21091235Chemical Composition, Antibacterial and Phytotoxic Activities of Peganum harmala Seed Essential Oils from Five Different Localities in Northern AfricaIda Apostolico0Luigi Aliberti1Lucia Caputo2Vincenzo De Feo3Florinda Fratianni4Filomena Nazzaro5Lucèia Fàtima Souza6Maroua Khadhr7Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano (Salerno), ItalyDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano (Salerno), ItalyDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano (Salerno), ItalyDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano (Salerno), ItalyIstituto di Scienze dell’Alimentazione, Consiglio Nazionale delle Ricerche (ISA-CNR), via Roma 64, 83100 Avellino, ItalyIstituto di Scienze dell’Alimentazione, Consiglio Nazionale delle Ricerche (ISA-CNR), via Roma 64, 83100 Avellino, ItalyDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano (Salerno), ItalyUnité de Recherche de Biochimie des Lipides et Principes Actifs des Plantes, 2092 Faculté des Sciences de Tunis, TunisiaPeganum harmala L., also known as Syrian rue or Pègano, is a herbaceous plant belonging to the Zygohpyllaceae family, and is widely used in traditional medicine. The chemical composition of essential oils of P. harmala seeds from five different regions of Northern Africa (Algeria, Egypt, Libya, Morocco and Tunisia) was studied by GC and GC-MS analyses. A total of 105 compounds were identified, the main components being oxygenated monoterpenes and oxygenated sesquiterpenes. Eugenol is the main component in all oils. The antimicrobial activity of the essential oils was assayed against some bacterial strains: Staphylococcus aureus (DSM 25693), Bacillus cereus (DSM 4313), Bacillus cereus (DSM4384), Escherichia coli (DMS 857) and Pseudomonas aeruginosa (ATCC 50071). All the oils showed different inhibitory activity. In the twentieth century this is an important result; we need possible new botanical drugs because the problem of resistance to antimicrobial drugs has become apparent. Moreover, the essential oils were evaluated for their possible in vitro phytotoxic activity against germination and initial radicle growth of Raphanus sativus L., Lepidium sativum L., and Ruta graveolens L. The results showed that both germination and radical elongation were sensitive to the oils.http://www.mdpi.com/1420-3049/21/9/1235Peganum harmalaessential oilantibacterial activityphytotoxic activity |
| spellingShingle | Ida Apostolico Luigi Aliberti Lucia Caputo Vincenzo De Feo Florinda Fratianni Filomena Nazzaro Lucèia Fàtima Souza Maroua Khadhr Chemical Composition, Antibacterial and Phytotoxic Activities of Peganum harmala Seed Essential Oils from Five Different Localities in Northern Africa Molecules Peganum harmala essential oil antibacterial activity phytotoxic activity |
| title | Chemical Composition, Antibacterial and Phytotoxic Activities of Peganum harmala Seed Essential Oils from Five Different Localities in Northern Africa |
| title_full | Chemical Composition, Antibacterial and Phytotoxic Activities of Peganum harmala Seed Essential Oils from Five Different Localities in Northern Africa |
| title_fullStr | Chemical Composition, Antibacterial and Phytotoxic Activities of Peganum harmala Seed Essential Oils from Five Different Localities in Northern Africa |
| title_full_unstemmed | Chemical Composition, Antibacterial and Phytotoxic Activities of Peganum harmala Seed Essential Oils from Five Different Localities in Northern Africa |
| title_short | Chemical Composition, Antibacterial and Phytotoxic Activities of Peganum harmala Seed Essential Oils from Five Different Localities in Northern Africa |
| title_sort | chemical composition antibacterial and phytotoxic activities of peganum harmala seed essential oils from five different localities in northern africa |
| topic | Peganum harmala essential oil antibacterial activity phytotoxic activity |
| url | http://www.mdpi.com/1420-3049/21/9/1235 |
| work_keys_str_mv | AT idaapostolico chemicalcompositionantibacterialandphytotoxicactivitiesofpeganumharmalaseedessentialoilsfromfivedifferentlocalitiesinnorthernafrica AT luigialiberti chemicalcompositionantibacterialandphytotoxicactivitiesofpeganumharmalaseedessentialoilsfromfivedifferentlocalitiesinnorthernafrica AT luciacaputo chemicalcompositionantibacterialandphytotoxicactivitiesofpeganumharmalaseedessentialoilsfromfivedifferentlocalitiesinnorthernafrica AT vincenzodefeo chemicalcompositionantibacterialandphytotoxicactivitiesofpeganumharmalaseedessentialoilsfromfivedifferentlocalitiesinnorthernafrica AT florindafratianni chemicalcompositionantibacterialandphytotoxicactivitiesofpeganumharmalaseedessentialoilsfromfivedifferentlocalitiesinnorthernafrica AT filomenanazzaro chemicalcompositionantibacterialandphytotoxicactivitiesofpeganumharmalaseedessentialoilsfromfivedifferentlocalitiesinnorthernafrica AT luceiafatimasouza chemicalcompositionantibacterialandphytotoxicactivitiesofpeganumharmalaseedessentialoilsfromfivedifferentlocalitiesinnorthernafrica AT marouakhadhr chemicalcompositionantibacterialandphytotoxicactivitiesofpeganumharmalaseedessentialoilsfromfivedifferentlocalitiesinnorthernafrica |