Relative frequency of Human T-cell Lymphotropic Virus I/II in HIV/AIDS patients
Background: Human T-cell lymphotropic virus HTLV-I/II is a retrovirus that has been associated with different diseases. HTLV-I/II routes of transmissions are exposure to contaminated blood, blood transfusion, needle sharing, breast feeding, and sexual contact. The seroprevalence of HTLV-I/II in HIV...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | Advanced Biomedical Research |
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| Online Access: | http://www.advbiores.net/article.asp?issn=2277-9175;year=2014;volume=3;issue=1;spage=8;epage=8;aulast=Meidani |
| _version_ | 1818315715054141440 |
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| author | Mohsen Meidani Nooshin Ahmadi Bahareh Jamali Zahra Askarian |
| author_facet | Mohsen Meidani Nooshin Ahmadi Bahareh Jamali Zahra Askarian |
| author_sort | Mohsen Meidani |
| collection | DOAJ |
| description | Background: Human T-cell lymphotropic virus HTLV-I/II is a retrovirus that has been associated with different diseases. HTLV-I/II routes of transmissions are exposure to contaminated blood, blood transfusion, needle sharing, breast feeding, and sexual contact. The seroprevalence of HTLV-I/II in HIV infected patients has not been well characterized in Iran. We conducted a serological survey to determine the relative frequency of HTLV-I/II in HIV+/AIDS and healthy blood donors in Isfahan.
Materials and Methods: In this cross-sectional study, we compare the relative frequency of HTLV-I/II in HIV+/AIDS group (56 persons) with asymptomatic blood donors (57 persons) in Isfahan. Participant completed the questionnaires that include demographic information, age, sex, and sexual partnership during last 6 months, sexual behavior and past history of blood transfusion or other blood products. We confirm the HIV+ status in patients group with western blot test. Evaluation of HTLV-I/II were done using ELISA test with DRAPIO third generation kit. Questionnaire data and laboratory results were analyzed by SPSS18.
Results: During the period of 2010-2011, a total of 56 HIV-infected patients and 57 healthy persons participated in this study. Among HIV positive patients, one person had positive test for HTILV-I/II representing the relative frequency of 1.8%, and in healthy individuals none of them were positive.
Conclusion: In our survey, relative frequency of HTLV-I/II was 1.8% in HIV+ patients. This study reveals that relative frequency of HTLV-I/II in HIV positive patients is considerable but determining the need for screening of HTLV-I/II requires further investigation. |
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| format | Article |
| id | doaj.art-187c23484ebc4da190c333598e3c5320 |
| institution | Directory Open Access Journal |
| issn | 2277-9175 2277-9175 |
| language | English |
| last_indexed | 2024-12-13T09:09:56Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Advanced Biomedical Research |
| spelling | doaj.art-187c23484ebc4da190c333598e3c53202022-12-21T23:52:58ZengWolters Kluwer Medknow PublicationsAdvanced Biomedical Research2277-91752277-91752014-01-01318810.4103/2277-9175.124635Relative frequency of Human T-cell Lymphotropic Virus I/II in HIV/AIDS patientsMohsen MeidaniNooshin AhmadiBahareh JamaliZahra AskarianBackground: Human T-cell lymphotropic virus HTLV-I/II is a retrovirus that has been associated with different diseases. HTLV-I/II routes of transmissions are exposure to contaminated blood, blood transfusion, needle sharing, breast feeding, and sexual contact. The seroprevalence of HTLV-I/II in HIV infected patients has not been well characterized in Iran. We conducted a serological survey to determine the relative frequency of HTLV-I/II in HIV+/AIDS and healthy blood donors in Isfahan. Materials and Methods: In this cross-sectional study, we compare the relative frequency of HTLV-I/II in HIV+/AIDS group (56 persons) with asymptomatic blood donors (57 persons) in Isfahan. Participant completed the questionnaires that include demographic information, age, sex, and sexual partnership during last 6 months, sexual behavior and past history of blood transfusion or other blood products. We confirm the HIV+ status in patients group with western blot test. Evaluation of HTLV-I/II were done using ELISA test with DRAPIO third generation kit. Questionnaire data and laboratory results were analyzed by SPSS18. Results: During the period of 2010-2011, a total of 56 HIV-infected patients and 57 healthy persons participated in this study. Among HIV positive patients, one person had positive test for HTILV-I/II representing the relative frequency of 1.8%, and in healthy individuals none of them were positive. Conclusion: In our survey, relative frequency of HTLV-I/II was 1.8% in HIV+ patients. This study reveals that relative frequency of HTLV-I/II in HIV positive patients is considerable but determining the need for screening of HTLV-I/II requires further investigation.http://www.advbiores.net/article.asp?issn=2277-9175;year=2014;volume=3;issue=1;spage=8;epage=8;aulast=MeidaniAIDSHIVHTLV-I/IIIran |
| spellingShingle | Mohsen Meidani Nooshin Ahmadi Bahareh Jamali Zahra Askarian Relative frequency of Human T-cell Lymphotropic Virus I/II in HIV/AIDS patients Advanced Biomedical Research AIDS HIV HTLV-I/II Iran |
| title | Relative frequency of Human T-cell Lymphotropic Virus I/II in HIV/AIDS patients |
| title_full | Relative frequency of Human T-cell Lymphotropic Virus I/II in HIV/AIDS patients |
| title_fullStr | Relative frequency of Human T-cell Lymphotropic Virus I/II in HIV/AIDS patients |
| title_full_unstemmed | Relative frequency of Human T-cell Lymphotropic Virus I/II in HIV/AIDS patients |
| title_short | Relative frequency of Human T-cell Lymphotropic Virus I/II in HIV/AIDS patients |
| title_sort | relative frequency of human t cell lymphotropic virus i ii in hiv aids patients |
| topic | AIDS HIV HTLV-I/II Iran |
| url | http://www.advbiores.net/article.asp?issn=2277-9175;year=2014;volume=3;issue=1;spage=8;epage=8;aulast=Meidani |
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