Kleine-Levin Syndorme: aetiology and pathogenesis, symptoms, diagnosis and treatment
AIM: The aim of the study is to present the aetiology, pathogenesis, symptoms, diagnosis and treatment of Kleine-Levin syndrome (KLS). VIEW: Kleine-Levin syndrome is an extremely rare disease entity that consists of attacks of hypersomnia, cognitive and behavioural disorders, hyperphagia and hypers...
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2018-08-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/26354 |
| _version_ | 1828401666730229760 |
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| author | Kamila Tuzim Tomasz Tuzim Magdalena Urbańczuk Marcin Urbańczuk Katarzyna Schab |
| author_facet | Kamila Tuzim Tomasz Tuzim Magdalena Urbańczuk Marcin Urbańczuk Katarzyna Schab |
| author_sort | Kamila Tuzim |
| collection | DOAJ |
| description | AIM: The aim of the study is to present the aetiology, pathogenesis, symptoms, diagnosis and treatment of Kleine-Levin syndrome (KLS).
VIEW: Kleine-Levin syndrome is an extremely rare disease entity that consists of attacks of hypersomnia, cognitive and behavioural disorders, hyperphagia and hypersexuality, which are alternated with asymptomatic intervals. The prevalence of this disease, whose etiopathogenesis has not been known yet, all over the world oscillates around 1-5 cases/1,000,000 inhabitants, with predilection for male gender, mainly during the puberty period. Lack of objective diagnostic methods implicates frequent diagnostic errors in KLS. What is more, up to now, an unequivocal position of experts concerning pharmacotherapy of this disease has not been established yet. However, prognosis seems to be favourable as the following episodes become rarer, of weaker intensity up to their complete remission in the majority of patients.
CONCLUSION: Further research of aetiology and pharmacological treatment of KLS is needed. |
| first_indexed | 2024-12-10T09:50:03Z |
| format | Article |
| id | doaj.art-187d361809944a88b6076ef1360d41a5 |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-12-10T09:50:03Z |
| publishDate | 2018-08-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-187d361809944a88b6076ef1360d41a52022-12-22T01:53:41ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062018-08-0188Kleine-Levin Syndorme: aetiology and pathogenesis, symptoms, diagnosis and treatmentKamila Tuzim0Tomasz Tuzim1Magdalena Urbańczuk2Marcin Urbańczuk3Katarzyna Schab4Chair and Department of Clinical Pathomorphology of the Medical University of LublinSanus Specialist Hospital, ul. Wojska Polskiego 4, Stalowa Wola, Poland;Chair and Department of Clinical Pathomorphology of the Medical University of LublinChair and Department of Family Medicine of the Medical University of Lublin, ul. Langiewicza 6 a, Lublin 20-032, Poland;Chair and Department of Clinical Immunology of the Medical University of Lublin, ul. Chodźki 4 a, Lublin 20-093, Poland;AIM: The aim of the study is to present the aetiology, pathogenesis, symptoms, diagnosis and treatment of Kleine-Levin syndrome (KLS). VIEW: Kleine-Levin syndrome is an extremely rare disease entity that consists of attacks of hypersomnia, cognitive and behavioural disorders, hyperphagia and hypersexuality, which are alternated with asymptomatic intervals. The prevalence of this disease, whose etiopathogenesis has not been known yet, all over the world oscillates around 1-5 cases/1,000,000 inhabitants, with predilection for male gender, mainly during the puberty period. Lack of objective diagnostic methods implicates frequent diagnostic errors in KLS. What is more, up to now, an unequivocal position of experts concerning pharmacotherapy of this disease has not been established yet. However, prognosis seems to be favourable as the following episodes become rarer, of weaker intensity up to their complete remission in the majority of patients. CONCLUSION: Further research of aetiology and pharmacological treatment of KLS is needed.https://apcz.umk.pl/JEHS/article/view/26354Kleine-Levin syndromesleep disorederhypersomniahyperphagiahypersexuality |
| spellingShingle | Kamila Tuzim Tomasz Tuzim Magdalena Urbańczuk Marcin Urbańczuk Katarzyna Schab Kleine-Levin Syndorme: aetiology and pathogenesis, symptoms, diagnosis and treatment Journal of Education, Health and Sport Kleine-Levin syndrome sleep disoreder hypersomnia hyperphagia hypersexuality |
| title | Kleine-Levin Syndorme: aetiology and pathogenesis, symptoms, diagnosis and treatment |
| title_full | Kleine-Levin Syndorme: aetiology and pathogenesis, symptoms, diagnosis and treatment |
| title_fullStr | Kleine-Levin Syndorme: aetiology and pathogenesis, symptoms, diagnosis and treatment |
| title_full_unstemmed | Kleine-Levin Syndorme: aetiology and pathogenesis, symptoms, diagnosis and treatment |
| title_short | Kleine-Levin Syndorme: aetiology and pathogenesis, symptoms, diagnosis and treatment |
| title_sort | kleine levin syndorme aetiology and pathogenesis symptoms diagnosis and treatment |
| topic | Kleine-Levin syndrome sleep disoreder hypersomnia hyperphagia hypersexuality |
| url | https://apcz.umk.pl/JEHS/article/view/26354 |
| work_keys_str_mv | AT kamilatuzim kleinelevinsyndormeaetiologyandpathogenesissymptomsdiagnosisandtreatment AT tomasztuzim kleinelevinsyndormeaetiologyandpathogenesissymptomsdiagnosisandtreatment AT magdalenaurbanczuk kleinelevinsyndormeaetiologyandpathogenesissymptomsdiagnosisandtreatment AT marcinurbanczuk kleinelevinsyndormeaetiologyandpathogenesissymptomsdiagnosisandtreatment AT katarzynaschab kleinelevinsyndormeaetiologyandpathogenesissymptomsdiagnosisandtreatment |