Testicular relapse of acute lymphoblastic leukemia
Contemporary chemotherapy regimens have led to improved survival and decreased incidence of testicular relapse for pediatric patients with acute lymphoblastic leukemia (ALL). Local therapies to the testes, such as radiotherapy and orchiectomy, are often not necessary given that high-dose chemotherap...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-09-01
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| Series: | Urology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214442023001353 |
| _version_ | 1827821558734782464 |
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| author | Alexandra Carolan Shane Batie Dinesh Rakheja Micah Jacobs Craig Peters Irina Stanasel |
| author_facet | Alexandra Carolan Shane Batie Dinesh Rakheja Micah Jacobs Craig Peters Irina Stanasel |
| author_sort | Alexandra Carolan |
| collection | DOAJ |
| description | Contemporary chemotherapy regimens have led to improved survival and decreased incidence of testicular relapse for pediatric patients with acute lymphoblastic leukemia (ALL). Local therapies to the testes, such as radiotherapy and orchiectomy, are often not necessary given that high-dose chemotherapy agents can overcome the relative blood-testis barrier. However, urologists should be aware of clinical scenarios involving ALL which still warrant testicular biopsy to guide management. Here, we present a case of a 12-year-old boy with high-risk pre-B cell ALL presenting with a testicular relapse and a clinical presentation overlapping with non-infectious epididymo-orchitis. |
| first_indexed | 2024-03-12T01:46:03Z |
| format | Article |
| id | doaj.art-188066f294a943e994644e14c60952c8 |
| institution | Directory Open Access Journal |
| issn | 2214-4420 |
| language | English |
| last_indexed | 2024-03-12T01:46:03Z |
| publishDate | 2023-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Urology Case Reports |
| spelling | doaj.art-188066f294a943e994644e14c60952c82023-09-09T04:55:20ZengElsevierUrology Case Reports2214-44202023-09-0150102449Testicular relapse of acute lymphoblastic leukemiaAlexandra Carolan0Shane Batie1Dinesh Rakheja2Micah Jacobs3Craig Peters4Irina Stanasel5University of Texas Southwestern Medical Center, Children's Health Texas, USAUniversity of Texas Southwestern Medical Center, Children's Health Texas, USAUniversity of Texas Southwestern Medical Center, Children's Health Texas, USAUniversity of Texas Southwestern Medical Center, Children's Health Texas, USAUniversity of Texas Southwestern Medical Center, Children's Health Texas, USACorresponding author. Children's Health Texas, 2350 N Stemmons Freeway, Ste 4300, Dallas, TX, 75207, USA.; University of Texas Southwestern Medical Center, Children's Health Texas, USAContemporary chemotherapy regimens have led to improved survival and decreased incidence of testicular relapse for pediatric patients with acute lymphoblastic leukemia (ALL). Local therapies to the testes, such as radiotherapy and orchiectomy, are often not necessary given that high-dose chemotherapy agents can overcome the relative blood-testis barrier. However, urologists should be aware of clinical scenarios involving ALL which still warrant testicular biopsy to guide management. Here, we present a case of a 12-year-old boy with high-risk pre-B cell ALL presenting with a testicular relapse and a clinical presentation overlapping with non-infectious epididymo-orchitis.http://www.sciencedirect.com/science/article/pii/S2214442023001353LeukemiaTesticular relapseTesticular biopsyPediatrics |
| spellingShingle | Alexandra Carolan Shane Batie Dinesh Rakheja Micah Jacobs Craig Peters Irina Stanasel Testicular relapse of acute lymphoblastic leukemia Urology Case Reports Leukemia Testicular relapse Testicular biopsy Pediatrics |
| title | Testicular relapse of acute lymphoblastic leukemia |
| title_full | Testicular relapse of acute lymphoblastic leukemia |
| title_fullStr | Testicular relapse of acute lymphoblastic leukemia |
| title_full_unstemmed | Testicular relapse of acute lymphoblastic leukemia |
| title_short | Testicular relapse of acute lymphoblastic leukemia |
| title_sort | testicular relapse of acute lymphoblastic leukemia |
| topic | Leukemia Testicular relapse Testicular biopsy Pediatrics |
| url | http://www.sciencedirect.com/science/article/pii/S2214442023001353 |
| work_keys_str_mv | AT alexandracarolan testicularrelapseofacutelymphoblasticleukemia AT shanebatie testicularrelapseofacutelymphoblasticleukemia AT dineshrakheja testicularrelapseofacutelymphoblasticleukemia AT micahjacobs testicularrelapseofacutelymphoblasticleukemia AT craigpeters testicularrelapseofacutelymphoblasticleukemia AT irinastanasel testicularrelapseofacutelymphoblasticleukemia |