Lack of the Actin Capping Protein, Eps8, Affects NMDA-Type Glutamate Receptor Function and Composition

Lack of the Actin Capping Protein, Eps8, Affects NMDA-Type Glutamate Receptor Function and Composition

Actin-based remodeling underlines spine morphogenesis and plasticity and is crucially involved in the processes that constantly reshape the circuitry of the adult brain in response to external stimuli, leading to learning and memory formation and supporting cognitive functions. Hence spine morpholog...

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Bibliographic Details
Main Authors: Raffaella Morini, Silvia Ferrara, Fabio Perrucci, Stefania Zambetti, Silvia Pelucchi, Elena Marcello, Fabrizio Gardoni, Flavia Antonucci, Michela Matteoli, Elisabetta Menna
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
EPS8
synapse
NMDA receptor
actin cytoskeleton
GluN2A
GluN2B
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00313/full

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