Matrix Metalloproteinase 13 Activity is Required for Normal and Hypoxia-Induced Precocious Hatching in Zebrafish Embryos

Matrix Metalloproteinase 13 Activity is Required for Normal and Hypoxia-Induced Precocious Hatching in Zebrafish Embryos

Hypoxia induces precocious hatching in zebrafish, but we do not have a clear understanding of the molecular mechanisms regulating the activation of the hatching enzyme or how these mechanisms trigger precocious hatching under unfavorable environmental conditions. Using immunohistochemistry, pharmaco...

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Bibliographic Details
Main Authors: Christopher D. Small, Megan el-Khoury, Ghislain Deslongchamps, Tillmann J. Benfey, Bryan D. Crawford
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Journal of Developmental Biology
Subjects:
hatching
matrix metalloproteinase 13 (mmp13)
zebrafish
hypoxia
in vivo zymography
stress
developmental trade-off
Online Access:https://www.mdpi.com/2221-3759/8/1/3

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