Indocyanine green fluorescence imaging to assess bowel perfusion during totally laparoscopic surgery for colon cancer
Abstract Background To retrospectively evaluate the feasibility and safety of intraoperative assessment of bowel perfusion in totally laparoscopic surgery for colon cancer using indocyanine green fluorescence imaging (IGFI). Methods From October 2017 to June 2019, consecutive patients with colon can...
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| Format: | Article |
| Language: | English |
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BMC
2020-05-01
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| Series: | BMC Surgery |
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| Online Access: | http://link.springer.com/article/10.1186/s12893-020-00745-4 |
| _version_ | 1819013579041406976 |
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| author | Hao Su Hongliang Wu Mandula Bao Shou Luo Xuewei Wang Chuanduo Zhao Qian Liu Xishan Wang Zhixiang Zhou Haitao Zhou |
| author_facet | Hao Su Hongliang Wu Mandula Bao Shou Luo Xuewei Wang Chuanduo Zhao Qian Liu Xishan Wang Zhixiang Zhou Haitao Zhou |
| author_sort | Hao Su |
| collection | DOAJ |
| description | Abstract Background To retrospectively evaluate the feasibility and safety of intraoperative assessment of bowel perfusion in totally laparoscopic surgery for colon cancer using indocyanine green fluorescence imaging (IGFI). Methods From October 2017 to June 2019, consecutive patients with colon cancer who underwent totally laparoscopic surgery were enrolled retrospectively and grouped into the IGFI group (n = 84) and control group (n = 105). In the IGFI group, indocyanine green (ICG) was injected intravenously, and the bowel perfusion was observed using a fluorescence camera system prior to and after completion of the anastomosis. Results The two groups were demographically comparable. The IGFI group exhibited a significantly shorter operative time (p = 0.0374) while intraoperative blood loss did not significantly differ among the groups (p = 0.062). In the IGFI group, average time to perfusion fluorescence was 48.4 ± 14.0 s after ICG injection, and four patients (4.8%) were required to choose a more proximal point of resection due to the lack of adequate fluorescence at the point previously selected. There were no differences in terms of pathological outcomes, postoperative recovery and the postoperative complication rates between the groups (p>0.05). Conclusion IGFI shows promise as a safe and feasible tool to assess bowel perfusion during a totally laparoscopic surgery for colon cancer and may reduce the operative time. |
| first_indexed | 2024-12-21T02:02:11Z |
| format | Article |
| id | doaj.art-189981b7e91143fe853afa5fa4422988 |
| institution | Directory Open Access Journal |
| issn | 1471-2482 |
| language | English |
| last_indexed | 2024-12-21T02:02:11Z |
| publishDate | 2020-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Surgery |
| spelling | doaj.art-189981b7e91143fe853afa5fa44229882022-12-21T19:19:36ZengBMCBMC Surgery1471-24822020-05-012011710.1186/s12893-020-00745-4Indocyanine green fluorescence imaging to assess bowel perfusion during totally laparoscopic surgery for colon cancerHao Su0Hongliang Wu1Mandula Bao2Shou Luo3Xuewei Wang4Chuanduo Zhao5Qian Liu6Xishan Wang7Zhixiang Zhou8Haitao Zhou9Department of Colorectal Surgery, National Cancer Center/ National Clinical Research Center for Cancer/ Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical CollegeDepartment of Anesthesiology, National Cancer Center/ National Clinical Research Center for Cancer/ Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical CollegeDepartment of Colorectal Surgery, National Cancer Center/ National Clinical Research Center for Cancer/ Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical CollegeDepartment of Colorectal Surgery, National Cancer Center/ National Clinical Research Center for Cancer/ Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical CollegeDepartment of Colorectal Surgery, National Cancer Center/ National Clinical Research Center for Cancer/ Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical CollegeDepartment of Colorectal Surgery, National Cancer Center/ National Clinical Research Center for Cancer/ Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical CollegeDepartment of Colorectal Surgery, National Cancer Center/ National Clinical Research Center for Cancer/ Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical CollegeDepartment of Colorectal Surgery, National Cancer Center/ National Clinical Research Center for Cancer/ Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical CollegeDepartment of Colorectal Surgery, National Cancer Center/ National Clinical Research Center for Cancer/ Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical CollegeDepartment of Colorectal Surgery, National Cancer Center/ National Clinical Research Center for Cancer/ Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical CollegeAbstract Background To retrospectively evaluate the feasibility and safety of intraoperative assessment of bowel perfusion in totally laparoscopic surgery for colon cancer using indocyanine green fluorescence imaging (IGFI). Methods From October 2017 to June 2019, consecutive patients with colon cancer who underwent totally laparoscopic surgery were enrolled retrospectively and grouped into the IGFI group (n = 84) and control group (n = 105). In the IGFI group, indocyanine green (ICG) was injected intravenously, and the bowel perfusion was observed using a fluorescence camera system prior to and after completion of the anastomosis. Results The two groups were demographically comparable. The IGFI group exhibited a significantly shorter operative time (p = 0.0374) while intraoperative blood loss did not significantly differ among the groups (p = 0.062). In the IGFI group, average time to perfusion fluorescence was 48.4 ± 14.0 s after ICG injection, and four patients (4.8%) were required to choose a more proximal point of resection due to the lack of adequate fluorescence at the point previously selected. There were no differences in terms of pathological outcomes, postoperative recovery and the postoperative complication rates between the groups (p>0.05). Conclusion IGFI shows promise as a safe and feasible tool to assess bowel perfusion during a totally laparoscopic surgery for colon cancer and may reduce the operative time.http://link.springer.com/article/10.1186/s12893-020-00745-4Indocyanine greenFluorescence imagingTotally laparoscopyBowel perfusionAnastomotic leak |
| spellingShingle | Hao Su Hongliang Wu Mandula Bao Shou Luo Xuewei Wang Chuanduo Zhao Qian Liu Xishan Wang Zhixiang Zhou Haitao Zhou Indocyanine green fluorescence imaging to assess bowel perfusion during totally laparoscopic surgery for colon cancer BMC Surgery Indocyanine green Fluorescence imaging Totally laparoscopy Bowel perfusion Anastomotic leak |
| title | Indocyanine green fluorescence imaging to assess bowel perfusion during totally laparoscopic surgery for colon cancer |
| title_full | Indocyanine green fluorescence imaging to assess bowel perfusion during totally laparoscopic surgery for colon cancer |
| title_fullStr | Indocyanine green fluorescence imaging to assess bowel perfusion during totally laparoscopic surgery for colon cancer |
| title_full_unstemmed | Indocyanine green fluorescence imaging to assess bowel perfusion during totally laparoscopic surgery for colon cancer |
| title_short | Indocyanine green fluorescence imaging to assess bowel perfusion during totally laparoscopic surgery for colon cancer |
| title_sort | indocyanine green fluorescence imaging to assess bowel perfusion during totally laparoscopic surgery for colon cancer |
| topic | Indocyanine green Fluorescence imaging Totally laparoscopy Bowel perfusion Anastomotic leak |
| url | http://link.springer.com/article/10.1186/s12893-020-00745-4 |
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