Polymyositis: clinical investigation in two sisters
We present an investigation of a case of polymyositis affecting two sisters of one same parenthood. Their cases have been documented for almost two decades, being investigated by means of a diagnostic protocol which combined clinical findings as well as laboratorial, histopathological and image test...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Academia Brasileira de Neurologia (ABNEURO)
2002-09-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2002000400020&tlng=en |
| _version_ | 1818975165404413952 |
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| author | Margô Gomes de Oliveira Karnikowski Bruno Rodrigues Veloso Costa Oscar Francisco Sanchez Osella Otávio de Tolêdo Nóbrega |
| author_facet | Margô Gomes de Oliveira Karnikowski Bruno Rodrigues Veloso Costa Oscar Francisco Sanchez Osella Otávio de Tolêdo Nóbrega |
| author_sort | Margô Gomes de Oliveira Karnikowski |
| collection | DOAJ |
| description | We present an investigation of a case of polymyositis affecting two sisters of one same parenthood. Their cases have been documented for almost two decades, being investigated by means of a diagnostic protocol which combined clinical findings as well as laboratorial, histopathological and image tests. In both cases, clinical manifestations started in childhood, without signs of involvement of the central and peripheral nervous system. Both patients proved to respond to a therapeutics based on corticosteroids. The degree of relatedness between their parents corroborate the notion that genetic factors may contribute to the development of the disease. |
| first_indexed | 2024-12-20T15:51:37Z |
| format | Article |
| id | doaj.art-189d8d5fdbd149b99cb957be07b869b4 |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-12-20T15:51:37Z |
| publishDate | 2002-09-01 |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-189d8d5fdbd149b99cb957be07b869b42022-12-21T19:34:39ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42272002-09-01603A62462710.1590/S0004-282X2002000400020Polymyositis: clinical investigation in two sistersMargô Gomes de Oliveira Karnikowski0Bruno Rodrigues Veloso Costa1Oscar Francisco Sanchez Osella2Otávio de Tolêdo Nóbrega3Universidade Católica de BrasíliaUniversidade Católica de BrasíliaUniversidade Católica de BrasíliaUniversidade Católica de BrasíliaWe present an investigation of a case of polymyositis affecting two sisters of one same parenthood. Their cases have been documented for almost two decades, being investigated by means of a diagnostic protocol which combined clinical findings as well as laboratorial, histopathological and image tests. In both cases, clinical manifestations started in childhood, without signs of involvement of the central and peripheral nervous system. Both patients proved to respond to a therapeutics based on corticosteroids. The degree of relatedness between their parents corroborate the notion that genetic factors may contribute to the development of the disease.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2002000400020&tlng=enpolymyositisinflammatory myopathy |
| spellingShingle | Margô Gomes de Oliveira Karnikowski Bruno Rodrigues Veloso Costa Oscar Francisco Sanchez Osella Otávio de Tolêdo Nóbrega Polymyositis: clinical investigation in two sisters Arquivos de Neuro-Psiquiatria polymyositis inflammatory myopathy |
| title | Polymyositis: clinical investigation in two sisters |
| title_full | Polymyositis: clinical investigation in two sisters |
| title_fullStr | Polymyositis: clinical investigation in two sisters |
| title_full_unstemmed | Polymyositis: clinical investigation in two sisters |
| title_short | Polymyositis: clinical investigation in two sisters |
| title_sort | polymyositis clinical investigation in two sisters |
| topic | polymyositis inflammatory myopathy |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2002000400020&tlng=en |
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