Development of an interfering peptide M1-20 with potent anti-cancer effects by targeting FOXM1
Abstract Disrupting protein–protein interactions (PPIs) has emerged as a promising strategy for cancer drug development. Interfering peptides disrupting PPIs can be rationally designed based on the structures of natural sequences mediating these interactions. Transcription factor FOXM1 overexpresses...
Main Authors: | Huitong Bu, Xianling Lan, Haojie Cheng, Chaozhu Pei, Min Ouyang, Yan Chen, Xiaoqin Huang, Li Yu, Yongjun Tan |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-08-01
|
Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-023-06056-9 |
Similar Items
-
The development of an anti-cancer peptide M1-21 targeting transcription factor FOXM1
by: Haojie Cheng, et al.
Published: (2023-06-01) -
Comprehensive analysis of FOXM1 immune infiltrates, m6a, glycolysis and ceRNA network in human hepatocellular carcinoma
by: Ziwu Xu, et al.
Published: (2023-05-01) -
FOXM1: Functional Roles of FOXM1 in Non-Malignant Diseases
by: Zhenwang Zhang, et al.
Published: (2023-05-01) -
FoxM1 is Upregulated in Osteosarcoma and Inhibition of FoxM1 Decreases Osteosarcoma Cell Proliferation, Migration, and Invasion
by: Zhu X, et al.
Published: (2020-10-01) -
Identification of peptides interfering with the LRRK2/PP1 interaction.
by: Chang Zhi Dong, et al.
Published: (2020-01-01)