Stationary-Phase Persisters to Ofloxacin Sustain DNA Damage and Require Repair Systems Only during Recovery
ABSTRACT Chronic infections are a serious health care problem, and bacterial persisters have been implicated in infection reoccurrence. Progress toward finding antipersister therapies has been slow, in part because of knowledge gaps regarding the physiology of these rare phenotypic variants. Evidenc...
Main Authors: | Katherine G. Völzing, Mark P. Brynildsen |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2015-10-01
|
Series: | mBio |
Online Access: | https://journals.asm.org/doi/10.1128/mBio.00731-15 |
Similar Items
-
Erratum: Inhibition of stationary phase respiration impairs persister formation in E. coli
by: Mehmet A. Orman, et al.
Published: (2016-02-01) -
Fluoroquinolone Persistence in <i>Escherichia coli</i> Requires DNA Repair despite Differing between Starving Populations
by: Annabel S. Lemma, et al.
Published: (2022-01-01) -
Stationary phase persister formation in Escherichia coli can be suppressed by piperacillin and PBP3 inhibition
by: Sandra J. Aedo, et al.
Published: (2019-06-01) -
Differential impacts of DNA repair machinery on fluoroquinolone persisters with different chromosome abundances
by: Juechun Tang, et al.
Published: (2024-05-01) -
The role of metabolism in bacterial persistence
by: Stephanie M. Amato, et al.
Published: (2014-03-01)