Endothelin‐converting enzyme‐1c promotes stem cell traits and aggressiveness in colorectal cancer cells

Endothelin‐converting enzyme‐1c promotes stem cell traits and aggressiveness in colorectal cancer cells

Endothelin‐1 is a mitogenic peptide that activates several proliferation, survival, and invasiveness pathways. The effects of endothelin‐1 rely on its activation by endothelin‐converting enzyme‐1 (ECE1), which is expressed as four isoforms with different cytoplasmic N termini. Recently, isoform ECE1...

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Bibliographic Details
Main Authors: Pablo Pérez‐Moreno, Sebastián Indo, Ignacio Niechi, Hernán Huerta, Pablo Cabello, Lilian Jara, Francisco Aguayo, Manuel Varas‐Godoy, Verónica A. Burzio, Julio C. Tapia
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:Molecular Oncology
Subjects:
CK2
phosphorylation
endothelin‐1
endothelin‐converting enzyme
cancer stem cell
aggressiveness
Online Access:https://doi.org/10.1002/1878-0261.12609

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