Residential radon and lung cancer: a cohort study in Galicia, Spain
Case-control studies show an association between residential radon and lung cancer. The aim of this paper is to investigate this association through a cohort study. We designed an ambispective cohort study using the Galician radon map, Spain, with controls drawn from a previous case-control study. S...
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| Format: | Article |
| Language: | English |
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Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz
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| Series: | Cadernos de Saúde Pública |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2017000605007&lng=en&tlng=en |
| _version_ | 1819264899331653632 |
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| author | Raquel Barbosa-Lorenzo Alberto Ruano-Ravina Sara Cerdeira-Caramés Mónica Raíces-Aldrey Juan M. Barros-Dios |
| author_facet | Raquel Barbosa-Lorenzo Alberto Ruano-Ravina Sara Cerdeira-Caramés Mónica Raíces-Aldrey Juan M. Barros-Dios |
| author_sort | Raquel Barbosa-Lorenzo |
| collection | DOAJ |
| description | Case-control studies show an association between residential radon and lung cancer. The aim of this paper is to investigate this association through a cohort study. We designed an ambispective cohort study using the Galician radon map, Spain, with controls drawn from a previous case-control study. Subjects were recruited between 2002 and 2009. The data were cross-checked to ascertain lung cancer incidence and then analysed using a Cox regression model. A total of 2,127 subjects participated; 24 lung cancer cases were identified; 76.6% of subjects were drawn from the radon map. The adjusted hazard ratio was 1.2 (95%CI: 0.5-2.8) for the category of subjects exposed to 50Bq/m3 or more. This risk rose when subjects from the case-control study were analyzed separately. In conclusion, we did not observe any statistically significant association between residential radon exposure and lung cancer; however, it appears that with a sample of greater median age (such as participants from the case-control study), the risk of lung cancer would have been higher. |
| first_indexed | 2024-12-23T20:36:49Z |
| format | Article |
| id | doaj.art-18a9a3e7769b45668285e98d4b475821 |
| institution | Directory Open Access Journal |
| issn | 1678-4464 |
| language | English |
| last_indexed | 2024-12-23T20:36:49Z |
| publisher | Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz |
| record_format | Article |
| series | Cadernos de Saúde Pública |
| spelling | doaj.art-18a9a3e7769b45668285e98d4b4758212022-12-21T17:32:02ZengEscola Nacional de Saúde Pública, Fundação Oswaldo CruzCadernos de Saúde Pública1678-446433610.1590/0102-311x00189415S0102-311X2017000605007Residential radon and lung cancer: a cohort study in Galicia, SpainRaquel Barbosa-LorenzoAlberto Ruano-RavinaSara Cerdeira-CaramésMónica Raíces-AldreyJuan M. Barros-DiosCase-control studies show an association between residential radon and lung cancer. The aim of this paper is to investigate this association through a cohort study. We designed an ambispective cohort study using the Galician radon map, Spain, with controls drawn from a previous case-control study. Subjects were recruited between 2002 and 2009. The data were cross-checked to ascertain lung cancer incidence and then analysed using a Cox regression model. A total of 2,127 subjects participated; 24 lung cancer cases were identified; 76.6% of subjects were drawn from the radon map. The adjusted hazard ratio was 1.2 (95%CI: 0.5-2.8) for the category of subjects exposed to 50Bq/m3 or more. This risk rose when subjects from the case-control study were analyzed separately. In conclusion, we did not observe any statistically significant association between residential radon exposure and lung cancer; however, it appears that with a sample of greater median age (such as participants from the case-control study), the risk of lung cancer would have been higher.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2017000605007&lng=en&tlng=enRadônioCarcinógenos AmbientaisExposição à RadiaçãoNeoplasias Pulmonares |
| spellingShingle | Raquel Barbosa-Lorenzo Alberto Ruano-Ravina Sara Cerdeira-Caramés Mónica Raíces-Aldrey Juan M. Barros-Dios Residential radon and lung cancer: a cohort study in Galicia, Spain Cadernos de Saúde Pública Radônio Carcinógenos Ambientais Exposição à Radiação Neoplasias Pulmonares |
| title | Residential radon and lung cancer: a cohort study in Galicia, Spain |
| title_full | Residential radon and lung cancer: a cohort study in Galicia, Spain |
| title_fullStr | Residential radon and lung cancer: a cohort study in Galicia, Spain |
| title_full_unstemmed | Residential radon and lung cancer: a cohort study in Galicia, Spain |
| title_short | Residential radon and lung cancer: a cohort study in Galicia, Spain |
| title_sort | residential radon and lung cancer a cohort study in galicia spain |
| topic | Radônio Carcinógenos Ambientais Exposição à Radiação Neoplasias Pulmonares |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2017000605007&lng=en&tlng=en |
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