Clk/STY (cdc2-like kinase 1) and Akt regulate alternative splicing and adipogenesis in 3T3-L1 pre-adipocytes.

Clk/STY (cdc2-like kinase 1) and Akt regulate alternative splicing and adipogenesis in 3T3-L1 pre-adipocytes.

The development of adipocytes from their progenitor cells requires the action of growth factors signaling to transcription factors to induce the expression of adipogenic proteins leading to the accumulation of lipid droplets, induction of glucose transport, and secretion of adipokines signaling meta...

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Bibliographic Details
Main Authors: Pengfei Li, Gay Carter, Jacqueline Romero, Kathryn M Gower, James Watson, Niketa A Patel, Denise R Cooper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3537621?pdf=render

Internet

http://europepmc.org/articles/PMC3537621?pdf=render

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